Results 31 to 40 of about 18,376 (272)
The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP. [PDF]
DevelopmentSharma R +8 more
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Fluid-structure interaction modelling of neighboring tubes with primary cilium analysis
Mathematical Biosciences and Engineering, 2023 We have developed a numerical model of two osculating cylindrical elastic renal tubules to investigate the impact of neighboring tubules on the stress applied to a primary cilium.
Nerion Zekaj +2 more
doaj +1 more source
The primary cilium at a glance [PDF]
Journal of Cell Science, 2010 The primary cilium, which was first so named by Sergei Sorokin ([Sorokin, 1968][1]), is a solitary organelle that emanates from the cell surface of most mammalian cell types during growth arrest.
Satir, Peter +2 more
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Frontiers in Cell and Developmental Biology, 2021 Primary cilia are solitary, microtubule-based protrusions surrounded by a ciliary membrane equipped with selected receptors that orchestrate important signaling pathways that control cell growth, differentiation, development and homeostasis. Depending on
Leticia Labat-de-Hoz +6 more
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Primary cilium and its role in tumorigenesis [PDF]
Journal of Zhejiang University (Medical Sciences), 2021 The primary cilium, a sensory organelle that protrudes from the surface of most eukaryotic cells, receives and transduces various critical signals that are essential for normal development and homeostasis. Structural or functional disruption of primary cilia causes a number of human diseases, including cancer.
Hongmei, Mao, Yi, Sun
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Organogenesis, 2014 The primary cilium is an antenna-like organelle that plays a vital role in organ generation and maintenance. It protrudes from the cell surface where it receives signals from the surrounding environment and relays them into the cell. These signals are then integrated to give the required outputs in terms of proliferation, differentiation, migration and
Fry, Andrew M +2 more
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Role of Primary Cilia in Skeletal Disorders
Stem Cells International, 2022 Primary cilia are highly conserved microtubule-based organelles that project from the cell surface into the extracellular environment and play important roles in mechanosensation, mechanotransduction, polarity maintenance, and cell behaviors during organ
Xinhua Li +7 more
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Lengthening primary cilia enhances cellular mechanosensitivity [PDF]
European Cells & Materials, 2017 The primary cilium is a mechanosensor in a variety of mammalian cell types, initiating and directing intracellular signalling cascades in response to external stimuli.
M Spasic, CR Jacobs
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A Ciliary View of the Immunological Synapse
Cells, 2019 The primary cilium has gone from being a vestigial organelle to a crucial signaling hub of growing interest given the association between a group of human disorders, collectively known as ciliopathies, and defects in its structure or function.
Chiara Cassioli, Cosima T. Baldari
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Primary Cilia: The New Face of Craniofacial Research
Biomolecules, 2022 The primary cilium is a solitary, sensory organelle that extends from the surface of nearly every vertebrate cell, including craniofacial cells. This organelle converts chemical and physical external stimuli into intracellular signaling cascades and ...
Emily R. Moore
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