Results 31 to 40 of about 728,235 (280)

Associations between purine metabolites and clinical symptoms in schizophrenia [PDF]

, 2012
Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology
Debra M. Montrose, George G. Dougherty, Jeffrey K. Yao, Joseph McEvoy, Kenji Hashimoto, Matcheri S. Keshavan, Ravinder D. Reddy, Rima Kaddurah-Daouk, Ruth Condray, Wayne R. Matson   +9 more
core   +6 more sources

Regulation of cytochrome P450 mRNA expression in primary porcine hepatocytes by selected secondary plant metabolites from chicory (Cichorium intybus L.) [PDF]

, 2013
Chicory (Cichorium intybus) has been shown to induce enzymes of pharmacokinetic relevance (cytochrome P450; CYP). The aim of this study was to investigate the effects of selected secondary plant metabolites with a global extract of chicory root, on the ...
Ekstrand, Bo, Klausen, Christina Lindgaard, Rasmussen, Martin Krøyer   +2 more
core   +1 more source

Primary Metabolite Profiling of Tinospora cordifolia

Natural Products Chemistry & Research, 2016
Plants are the sources of many bioactive compounds containing many primary metabolites like, carbohydrates (starch, sugar), proteins, phenols, ascorbic acid etc. are useful for flavoring, fragrances, insecticides, sweeteners and natural dyes (Kaufman).
Abhimanyu Sharma, Amla Batra
openaire   +1 more source

Optimized protocol to isolate primary mouse peritoneal macrophage metabolites

STAR Protocols, 2022
Peritoneal macrophages (PMs) have been shown to have higher stability compared to other macrophage subtypes. However, obtaining enough PMs from a single mouse is often a limitation for metabolomics analysis. Here, we describe a protocol to isolate metabolites from a small number of mouse primary PMs for 13C-stable glucose tracing and metabolomics.
Adam De Jesus, Carolina M. Pusec, Tivoli Nguyen, Farnaz Keyhani-Nejad, Peng Gao, Samuel E. Weinberg, Hossein Ardehali   +6 more
openaire   +3 more sources

Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress [PDF]

, 2014
Accepted: 8 January 2014 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Acknowledgments
Alfonso, Amparo, Alonso, Eva, Botana, Luis M, Ebel, Rainer, Houssen, Wael E, Jaspars, Marcel, Leirós, Marta, Rateb, Mostafa E, Rateb, Mostafa Ezzat Mohamed, Sánchez, Jon A   +9 more
core   +4 more sources

From Waste to Resource: Nutritional and Functional Potential of Borlotto Bean Pods (Phaseolus vulgaris L.)

Antioxidants
Borlotto bean pods, a by-product of Phaseolus vulgaris processing, represent a promising yet underexplored source of bioactive compounds. This study aimed to characterize the nutritional composition, phytochemical profile, and biological properties of a ...
Antonella Smeriglio, Martina Imbesi, Mariarosaria Ingegneri, Rossana Rando, Manuela Mandrone, Ilaria Chiocchio, Ferruccio Poli, Domenico Trombetta   +7 more
doaj   +1 more source

Serum 25-Hydroxyvitamin D and Intact Parathyroid Hormone Influence Muscle Outcomes in Children and Adolescents [PDF]

, 2018
Increases in 25-hydroxyvitamin D concentrations are shown to improve strength in adults; however, data in pediatric populations are scant and equivocal. In this ancillary study of a larger-scale, multi-sited, double-blind, randomized, placebo-controlled ...
Addison, Bergman, Bignotti, Bischoff-Ferrari, Boland, Buford, Cangussu, Carrillo, Ceglia, Ceglia, Close, DeLuca, Dhesi, El-Hajj Fuleihan, El-Hajj Fuleihan, Foo, Gerdhem, Gilsanz, Girgis, Glendenning, Goodpaster, Goran, Goswami, Gupta, Hansen, Haroon, Hassan-Smith, Hoaglin, Houston, Keihan Rodrigues Matsudo, Kwon, Lewis, Looker, Malina, Mansbach, Michael, Miljkovic-Gacic, Molenaar, Neinstein, Passeri, Pate, Pollock, Redzic, Rittweger, Rogol, Sinha, Swinford, Tanner, Templeton, Visser, Ward, Ward, Warden, Wind, Wolff, Yin   +55 more
core   +2 more sources

PRIMARY AND SECONDARY METABOLITES LASALLIA PENSYLVANICA

chemistry of plant raw material, 2019
Gyrophoric acid was isolated from thalluses of Lasallia pensylvanica and identification using IR, UV, MS spectrometry and differential scanning calorimetry. It was established that the content of gyrophoric acid in the lichen was 36 mg/g. It was shown that the gyrophoric acid exhibited antioxidant activity relative to the superoxide anion, NO, DPPH and
Igor' Vital'yevich Sleptsov, Il'ya Andreyevich Prokopiev, Alla Nikolayevna Zhuravskaya   +2 more
openaire   +3 more sources

The reliance of phytohormone biosynthesis on primary metabolite precursors

Journal of Plant Physiology, 2022
There is some debate as to whether phytohormone metabolites should be classified as primary or secondary metabolites. Phytohormones have profound effects on growth - a typical trait of primary metabolites - yet several of them are formed from secondary metabolite precursors.
Norma Fàbregas, Alisdair R. Fernie
openaire   +3 more sources

Citrus Pomace as a Source of Plant Complexes to Be Used in the Nutraceutical Field of Intestinal Inflammation

Antioxidants
This study aims to recover the main by-product of Citrus fruits processing, the raw pomace, known also as pastazzo, to produce plant complexes to be used in the treatment of inflammatory bowel disease (IBD). Food-grade extracts from orange (OE) and lemon
Mariarosaria Ingegneri, Maria Rita Braghini, Michela Piccione, Cristiano De Stefanis, Manuela Mandrone, Ilaria Chiocchio, Ferruccio Poli, Martina Imbesi, Anna Alisi, Antonella Smeriglio, Domenico Trombetta   +10 more
doaj   +1 more source