Rational a priori or Emotional a priori? Husserl and Scheler’s Criticisms of Kant Regarding the Foundation of Ethics [PDF]
, 2011 Based on the dispute between Protagoras and Socrates on the origin of ethics, one can ask the question of whether the principle of ethics is reason orfeeling/emotion, or whether ethics is grounded on reason or feeling/emotion.
Zhang, Wei
core
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Localizing Violations of the Principle of Sufficient Reason—Leibniz on the Modal Status of the PSR
Journal of Modern Philosophy, 2022 The Principle of Sufficient Reason (PSR)—the principle that everything has a reason—plays a central role in Leibniz’s philosophical system. It is rather difficult, however, to determine what Leibniz’s attitude towards the modal status of the PSR is.
Sebastian Bender
doaj +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Authors and open access publishing [PDF]
, 2004 Surveys were carried out to learn more about authors and open access publishing. Awareness of open access journals among those who had not published in them was quite high; awareness of "self-archiving" wasless.
Brown, Sheridan, Swan, Alma
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Comparative Study on the Degree of Dependence of Clarke’s and Sadra’s Arguments for the Existence of God on the Principle of Sufficient Reason [PDF]
حکمت و فلسفه, 2010 After briefly discussing the various versions of the Principle of Sufficient Reason (hereafter PSR), I argue that Clarke’s classic version of the Cosmological Arguments for the existence of God is rooted in the PSR, while Sadra’s so-called Siddigin ...
hasan hoseyni
doaj +1 more source
Towards a holographic theory of cosmology -- threads in a tapestry [PDF]
, 2013 In this Essay we address several fundamental issues in cosmology: What is the nature of dark energy and dark matter? Why is the dark sector so different from ordinary matter?
Ng, Y. Jack
core +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
HOW THE PRINCIPLE OF SUFFICIENT REASON UNDERMINES THE COSMOLOGICAL ARGUMENT
KriterionMy aim here is to show how the Cosmological Argument (CA) is undermined by one of its own premises: the Principle of Sufficient Reason (PSR). Firstly, I explain the type of CA that I am thinking about (I).
Sebastián Briceño
doaj +1 more source