Results 71 to 80 of about 166,272,513 (247)

On the Epistemology of the Precautionary Principle [PDF]

open access: yes, 2014
In this paper we present two distinctly epistemological puzzles that arise forone who aspires to defend the precautionary principle. The first puzzle involves anapplication of contextualism in epistemology; and the second puzzle concerns the task of ...
Carter, J.A.   +5 more
core   +2 more sources

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The Explanation of Second Analogy (Principle of Causality) in Critique of Pure Reason [PDF]

open access: yesحکمت اسرا, 2014
Kant's attention to the causality is due to conflicts of processes of objectification in subjective concept of causality. The question has always been along the doubts of philosophers in modern era about the duality of body and soul. Philosophers such as
mohammadhadi hazeri   +1 more
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

"The Sleep of Reason:" A Video Installation by Bill Viola

open access: yes, 1991
Photograph of the exhibition "'The Sleep of Reason:' A Video Installation by Bill Viola," November 14, 1991-February 9, 1992 held at the Dallas Museum of ...
Dallas Museum of Art
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Using the quantum probability ranking principle to rank interdependent documents [PDF]

open access: yes, 2010
A known limitation of the Probability Ranking Principle (PRP) is that it does not cater for dependence between documents. Recently, the Quantum Probability Ranking Principle (QPRP) has been proposed, which implicitly captures dependencies between ...
Azzopardi, L.   +5 more
core   +3 more sources

Examining Pancasila’s Position in the Public Reason Scheme: A Critical Analysis

open access: yesJurnal Politik, 2019
This research tries to review a number of ideas of some Indonesian scholars such as Yudi Latif, Franz Magnis-Suseno, and Syamsul Ma'arif, who saw and described the relationship between Pancasila and public reason, one of the popular political concepts in
Muhamad Iswardani Chaniago
doaj   +1 more source

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