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[The Propagation Hypothesis of Prion-like Protein Agregates in Neurodegenerative Diseases].

Brain and nerve = Shinkei kenkyu no shinpo, 2019
The most common neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis, are known to be protein-misfolding diseases, and characterized by the presence of disease-specific protein aggregates in neuronal and glial cells.
openaire   +1 more source

Prion-like propagation of Parkinson's disease

The Biomedical & Life Sciences Collection, 2014
openaire   +1 more source

Exosome-Mediated Prion-Like Propagation as a Complementary Mechanism of Metastatic Initiation

Background. Metastatic progression is shaped by clonal dissemination, Darwinian selection, and subclonal diversification. Yet multiregion genomic analyses reveal substantial divergence between primary tumors and metastatic lesionsincluding high burdens of private mutations and organ-adapted transcriptional programsthat invite exploration of ...
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Direct observation of prion-like propagation of misfolding in single protein molecules

Biophysical Journal, 2022
Krishna P. Neupane   +5 more
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Frontiers in Molecular Neuroscience, 2019
Steven S Plotkin   +2 more
exaly  

Toll-like receptor-mediated immune response inhibits prion propagation

Glia, 2016
Holger Wille, Judd Aiken, Valerie L. Sim
exaly  

The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders

International Journal of Molecular Sciences, 2020
Sabine Gilch
exaly  

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