Results 191 to 200 of about 5,185,837 (206)
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[The Propagation Hypothesis of Prion-like Protein Agregates in Neurodegenerative Diseases].
Brain and nerve = Shinkei kenkyu no shinpo, 2019The most common neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis, are known to be protein-misfolding diseases, and characterized by the presence of disease-specific protein aggregates in neuronal and glial cells.
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Decoding the Cellular Trafficking of Prion-like Proteins in Neurodegenerative Diseases
Neuroscience Bulletin, 2023Yongmei Xi, Zhen Zhong
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Prion-like propagation of Parkinson's disease
The Biomedical & Life Sciences Collection, 2014openaire +1 more source
Evidence piles Up for prion‐like propagation mechanisms in synucleinopathies
Movement Disorders, 2014openaire +2 more sources
Exosome-Mediated Prion-Like Propagation as a Complementary Mechanism of Metastatic Initiation
Background. Metastatic progression is shaped by clonal dissemination, Darwinian selection, and subclonal diversification. Yet multiregion genomic analyses reveal substantial divergence between primary tumors and metastatic lesionsincluding high burdens of private mutations and organ-adapted transcriptional programsthat invite exploration of ...openaire +1 more source
Direct observation of prion-like propagation of misfolding in single protein molecules
Biophysical Journal, 2022Krishna P. Neupane +5 more
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Toll-like receptor-mediated immune response inhibits prion propagation
Glia, 2016Holger Wille, Judd Aiken, Valerie L. Sim
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Prion propagation and toxicity in vivo occur in two distinct mechanistic phases
Nature, 2011John Collinge
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The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders
International Journal of Molecular Sciences, 2020Sabine Gilch
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