Results 111 to 120 of about 36,884 (188)

Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Chronic traumatic encephalopathy (CTE) is a tauopathy linked to repetitive head impacts. Factors influencing brain regional susceptibility to tau deposition and spreading remain unclear. METHODS We used three datasets: [18F]flortaucipir positron emission tomography (PET) in 157 former professional American football players and 53 ...
Tim L. T. Wiegand, Anna Rubinski, Leonard B. Jung, Nicolai Franzmeier, Hector Arciniega, Parsa Ravanfar, Anna Dewenter, Michael L. Alosco, Yorghos Tripodis, Yi Su, Hillary Protas, Alexander P. Lin, Ofer Pasternak, Kewei Chen, Michael J. Coleman, Sylvain Bouix, Charles H. Adler, Laura J. Balcer, Charles Bernick, Jeffrey L. Cummings, Robert A. Stern, Eric M. Reiman, Martha E. Shenton, Michael Ewers, Inga K. Koerte, for the DIAGNOSE CTE Research Project   +25 more
wiley   +1 more source

Mitochondrial NADK2‐dependent NADPH controls tau oligomer uptake in human neurons

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Reduced brain energy metabolism, mitochondria dysfunction, and extracellular tau oligomer buildup characterize Alzheimer's disease (AD), but how these phenomena cooperatively promote neurodegeneration is poorly understood. We now report that tau oligomers (TauOs) pathologically coordinate mitochondrial metabolism with increased ...
Evelyn Pardo, Taylor Kim, Horst Wallrabe, Kristine E. Zengeler, Vijay Kumar Sagar, Garnett Mingledorff, Xuehan Sun, Ammasi Periasamy, John R. Lukens, George S. Bloom, Andrés Norambuena   +10 more
wiley   +1 more source

Authorship and citation trends in dementia research: A path to equitable career development for scientists

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Women are increasingly entering the dementia research workforce, but they frequently fail to attain senior leadership positions in academia. Discrepancies in academic research outputs were investigated to guide equity‐focused policy recommendations.
Jayalakshmi Viswanathan, Diana Karamacoska, Lokendra S. Thakur, Mouna Sawan, Angela Gomez‐Arboledas, Ines Moreno‐Gonzalez, C. Elizabeth Shaaban, Sadaf A. Milani, Giedre Milinkeviciute, Samantha M. Loi, Anika Wuestefeld, Sindhuja T. Govindarajan, Audrey Low, Giovanna Carello‐Collar, Hom L. Shreshta, Sunnie Kenowsky, Claudia K. Suemoto, Michelle M. Mielke, Shana D. Stites   +18 more
wiley   +1 more source

Roles of prion proteins in mammalian development. [PDF]

Anim Cells Syst (Seoul)
Cheon YP, Ryou C, Svedružić ŽM.
europepmc   +1 more source

Prion Proteins Without the Glycophosphatidylinositol Anchor: Potential Biomarkers in Neurodegenerative Diseases. [PDF]

Biomark Insights, 2018
Kovač V, Čurin Šerbec V.
europepmc   +1 more source

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, Volume 73, Issue 3, Page 1115-1124, June 2026.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

Editorial: Prion and prion-like proteins in neurodegenerative diseases

Frontiers in Neuroscience, 2022
Mattia Toni, Simona Eleuteri
doaj   +1 more source

Different folding mechanisms in prion proteins from mammals with different disease susceptibility observed at the single-molecule level. [PDF]

Proc Natl Acad Sci U S A
Anand U, Patra S, Sekar RV, Garen CR, Woodside MT.   +4 more
europepmc   +1 more source

5‐Hydroxytryptamine Distribution Alteration in Both Neuron and Synapse of Tg(SOD1*G93A)1gur Mice: A Potential Intervention Candidate Strategy for Amyotrophic Lateral Sclerosis

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This study reveals that 5‐hydroxytryptamine (5‐HT) synapses in the spinal cord and 5‐HT neurons in the brainstem of the SOD1‐G93A amyotrophic lateral sclerosis (ALS) mouse model are significantly altered, showing a decrease in pre‐symptomatic stages but a marked increase as the disease progresses.
Lijun Zhou, Menghua Li, Qi Dai, Xiwang Liu, Cheng Li, Huifeng Jiao, Haili Pan, Renshi Xu   +7 more
wiley   +1 more source

Physiology of Cellular Prion Proteins in Reproduction. [PDF]

Dev Reprod
Svedružić ŽM, Ryou C, Choi D, Lee SH, Cheon YP.   +4 more
europepmc   +1 more source