Results 91 to 100 of about 1,067,103 (202)

Pro-opiomelanocortin gene delivery suppresses the growth of established Lewis lung carcinoma through a melanocortin-1 receptor-independent pathway

, 2012
Background: Pro-opiomelanocortin (POMC) is the precursor of several neuropeptides, such as corticotropin, melanocyte-stimulating hormone and the endogenous opioid (β-endorphin).
Dusting, GJ (15629489), Chen, SC (15490148), Liu, LF (15664229), Kung, ML (15664226), Tee, R (15514067), Tsai, HE (15664019), Weng, WT (15664364), Guei-Sheung Liu (14742562), Tai, MH (15664028)   +8 more
core  

Particular processing of pro-opiomelanocortin in Xenopus laevis intermediate pituitary Sequencing of α- and β-melanocyte-stimulating hormones

, 1989
α- and β-melanocyte-stimulating hormones (α-MSH and β-MSH) have been isolated from Xenopus laevis neurointermediate pituitary and microsequenced. Intracellular α-MSH is not N-acetylated after proteolytic processing of pro-opiomelanocortin in contrast to ...
Acher, R., G. Michel, J. Chauvet, R. Acher, Chauvet, M.T., Michel, G., Y. Rouillé, Chauvet, J., Rouillé, Y., M.T. Chauvet   +9 more
core   +1 more source

Hormonal regulation of the hypothalamic melanocortin system

Frontiers in Physiology, 2014
Regulation of energy homeostasis is fundamental for life. In animal species and humans, the Central Nervous System (CNS) plays a critical role in such regulation by integrating peripheral signals and modulating behavior and the activity of peripheral ...
Jung Dae eKim, Stephanie eLeyva, Sabrina eDiano   +2 more
doaj   +1 more source

Increase of Pro-opiomelanocortin mRNA Prior to Tyrosinase, Tyrosinase-Related Protein 1, Dopachrome Tautomerase, Pmel-17/gp100, and P-Protein mRNA in Human Skin After Ultraviolet B Irradiation

, 2002
In ultraviolet-induced tanning, the protein levels of various gene products critical for pigmentation (including tyrosinase and tyrosinase-related protein-1) are increased in response to ultraviolet B irradiation, but changes in mRNA levels of these ...
Kato, Tomomi, Katagiri, Takayuki, Motokawa, Tomonori, Tomita, Yasushi, Suzuki, Itaru, Nakamura, Eriko   +5 more
core   +1 more source

5-HT\(_{\text{2C}}\)Rs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis [PDF]

, 2008
Drugs activating 5-hydroxytryptamine 2C receptors (5-HT\(_{\text{2C}}\)Rs) potently suppress appetite, but the underlying mechanisms for these effects are not fully understood.
Heisler, Lora K., Xu, Yong, Williams, Kevin W., Lowell, Bradford, Elmquist, Joel K., Anderson, Jason G., Lowell, Bradford B., Choi, Michelle J., Zigman, Jeffrey M., Kohno, Daisuke, Lee, Charlotte E., Jones, Juli E.   +11 more
core   +1 more source

Developmental thyroid hormone action on pro-opiomelanocortin-expressing cells programs hypothalamic BMPR1A depletion and brown fat activation. [PDF]

J Mol Cell Biol, 2023
Wu Z, Martinez ME, DeMambro V, Francois M, Hernandez A.   +4 more
europepmc   +1 more source

Presence of pro-opiomelanocortin-related peptides in dog adrenal gland

, 1988
Coupling high performance liquid chromatography to specific radioimmunoassays, this study evaluates the presence of several pro-opiomelanocortin(POMC)-related peptides in dog adrenal gland.
facchinetti fabio
core  

Down-regulation of hypothalamic pro-opiomelanocortin (POMC) expression after weaning is associated with hyperphagia-induced obesity in JCR rats overexpressing neuropeptide Y

, 2013
We hypothesised that hypothalamic feeding-related neuropeptides are differentially expressed in obese-prone and lean-prone rats and trigger overeating-induced obesity.
Pierce, W. David, Russell, James C., Diane, Abdoulaye, Heth, C. Donald, Richard, Denis, Proctor, Spencer D., Vine, Donna F.   +6 more
core   +1 more source

Sex differences and the lack of effects of chemogenetic manipulation of pro-opiomelanocortin (POMC) neurons on alcohol consumption in male and female mice. [PDF]

Brain Res, 2022
Leyrer-Jackson JM, Hood LE, Olive MF.
europepmc   +1 more source

Loss of Autophagy in Pro-opiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation

, 2012
SummaryThe hypothalamic melanocortin system, which includes neurons that produce pro-opiomelanocortin (POMC)-derived peptides, is a major negative regulator of energy balance.
Coupé, Bérengère, Horvath, Tamas L., Bouret, Sebastien G., Dietrich, Marcelo O., Komatsu, Masaaki, Ishii, Yuko   +5 more
core   +1 more source