Results 101 to 110 of about 1,457,386 (196)

NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia.

open access: yes, 2010
Anorexia and weight loss are prevalent in infectious diseases. To investigate the molecular mechanisms underlying these phenomena, we established animal models of infection-associated anorexia by administrating bacterial and viral products ...
허만욱
core   +1 more source

Serotonin 2C Receptor Activates a Distinct Population of Arcuate Pro-opiomelanocortin Neurons via TRPC Channels

open access: yes, 2011
SummarySerotonin 2C receptors (5-HT2CRs) expressed by pro-opiomelanocortin (POMC) neurons of hypothalamic arcuate nucleus regulate food intake, energy homeostasis and glucose metabolism.
Kevin Wickman   +11 more
core   +1 more source

Regulation of Feeding Behavior and Body Weight by Orexigenic Neurons in the Arcuate Nucleus

open access: yesJournal of Obesity & Metabolic Syndrome
The arcuate nucleus of the hypothalamus is arguably the most important nucleus for regulating energy homeostasis and metabolism. Since its initial description in the human brain, its function in metabolic regulation has been studied extensively.
Yu Fu
doaj   +1 more source

Dysregulation of plasma pro-opiomelanocortin-related peptides in neurotic depression.

open access: yes, 1986
In order to assess whether a central hypothalamic impairment could account for the pro-opiomelanocortin (POMC)-related peptide over-secretion in depressive disorders, plasma B-lipotropin (B-LPH), B-endorphin (B-EP) and cortisol concentrations were ...
Nappi G.   +5 more
core   +2 more sources

Identification of the sorting signal motif within pro-opiomelanocortin for the regulated secretory pathway

open access: yes, 1995
Udgivelsesdato: 1995-Apr-14The NH2-terminal region of pro-opiomelanocortin (POMC) is highly conserved across species, having two disulfide bridges that cause the formation of an amphipathic hairpin loop structure between the 2nd and 3rd cysteine residues
Loh, Y P   +3 more
core   +1 more source

Gene-specific primers used for Real-Time PCR.

open access: yes, 2013
Ob-Rb, leptin receptor; SOCS3, suppressor of cytokine signaling 3; NPY, neuropeptide Y; AgRP, agouti-related peptide; POMC, pro-opiomelanocortin; CART; cocaine- and amphetamine-regulated transcript.
Xue-Ying Zhang (144147)   +2 more
core   +1 more source

Description of the DNA methylation of the hypothalamus-specific enhancers of the Pro-opiomelanocortin gene

open access: yes, 2009
Die mittels QTL-Scans erfasste Assoziation zwischen Markern im Bereich des Pro-Opiomelanocortin Locus und dem Körpergewicht, ohne dass im Gen selbst gelegene, funktionell bedeutsame Polymorphismen identifiziert werden konnten, rückt die transkriptionelle
Auler, Antje
core   +1 more source

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