Pro-opiomelanocortin (POMC) is expressed in two lineages of the pituitary, the anterior lobe corticotrophs and the intermediate lobe melanotrophs. POMC expression in these two lineages is highly dependent on the cell-restricted transcription factor Tpit.
L. Budry +3 more
semanticscholar +1 more source
Comparison the Effect of Eight-Week of Resistance and Combined Training on Pro-Opiomelanocortin Gene Expression in Brain Tissue and Insulin Resistance of Obese Wistar Rats [PDF]
Background and purpose: Studies have shown that exercise improves glucose uptake by acutely increasing insulin sensitivity. Additionally, acute exercise or adaptation to exercise training activates pro-opiomelanocortin (POMC) neurons, which affect ...
Amir Hossein Shahabi +2 more
doaj
Developmental thyroid hormone action on pro-opiomelanocortin-expressing cells programs hypothalamic BMPR1A depletion and brown fat activation. [PDF]
Wu Z +4 more
europepmc +1 more source
Human and murine PTX1/Ptx1 gene maps to the region for Treacher Collins Syndrome. [PDF]
Ptx1 belongs to an expanding family of bicoid-related vertebrate homeobox genes. These genes, like their Drosophila homolog, seem to play a role in the development of anterior structures and, in particular, the brain and facies. We report the chromosomal
Barbara Beatty +8 more
core +4 more sources
Hormonal regulation of the hypothalamic melanocortin system
Regulation of energy homeostasis is fundamental for life. In animal species and humans, the Central Nervous System (CNS) plays a critical role in such regulation by integrating peripheral signals and modulating behavior and the activity of peripheral ...
Jung Dae eKim +2 more
doaj +1 more source
Role of Leptin in Metabolic Adaptation During Cold Acclimation [PDF]
Chronic cold exposure stimulates thermogenesis in brown adipose tissue, resulting in fat mobilization and compensatory hyperphagia. Mostly, these physiological events are accompanied by a remarkable reduction in serum leptin levels ...
De-Hua Wang +3 more
core
Sex differences and the lack of effects of chemogenetic manipulation of pro-opiomelanocortin (POMC) neurons on alcohol consumption in male and female mice. [PDF]
Leyrer-Jackson JM, Hood LE, Olive MF.
europepmc +1 more source
The Melanocortin System in Control of Inflammation
Melanocortin peptides, the collective term for α-, β-, and γ-melanocyte-stimulating hormone (α-, β-, γ-MSH) and adrenocorticotropic hormone (ACTH), are elements of an ancient modulatory system.
Anna Catania +5 more
doaj +1 more source
Orexin A Enhances Pro-Opiomelanocortin Transcription Regulated by BMP-4 in Mouse Corticotrope AtT20 Cells. [PDF]
Fujisawa S +6 more
europepmc +1 more source
Biosynthesis of pituitary pro-opiomelanocortin hormones
Bibliography: p. 99-103.
openaire +2 more sources

