Results 71 to 80 of about 1,457,386 (196)

Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake

Cell & Bioscience, 2022
Background Central nervous system (CNS) control of metabolism plays a pivotal role in maintaining energy balance. In the brain, Glucagon-like peptide 1 (GLP-1), encoded by the proglucagon ‘Gcg’ gene, produced in a distinct population of neurons in the ...
Ishnoor Singh, Le Wang, Baijuan Xia, Ji Liu, Azeddine Tahiri, Abdelfattah El Ouaamari, Michael B. Wheeler, Zhiping P. Pang   +7 more
doaj   +1 more source

Early‐Life Betaine Supplementation Drives Sex‐Specific Metabolic Programming in Rats, Affecting FGF21 Signaling and Energy Balance

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
A maternal western diet (WD) and betaine supplementation during suckling influence metabolic programming. A maternal WD induced adverse metabolic effects in offspring, accompanied by altered FGF21‐related gene expression and decreased Akkermansia muciniphila abundance.
Rocío A. Martín‐Chamorro, Catalina A. Pomar, Andreu Palou, Catalina Picó, Ana M. Rodríguez   +4 more
wiley   +1 more source

ACTH in invertebrates: a molecule for all seasons [PDF]

Invertebrate Survival Journal, 2016
In vertebrate and invertebrate models, adrenocorticotropic hormone (ACTH) belongs to the melanocortin group of related peptides, which share a common precursor, pro-opiomelanocortin (POMC).
D Malagoli, E Ottaviani
doaj   +1 more source

PGC-1α expression in murine AgRP neurons regulates food intake and energy balance

Molecular Metabolism, 2016
Objective: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP) and pro-opiomelanocortin (POMC) neurons located in the arcuate nucleus of the hypothalamus.
Jonathan F. Gill, Julien Delezie, Gesa Santos, Christoph Handschin   +3 more
doaj   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

Neuropathic Pain Comorbid Cognitive Impairment and Vitamin D: A Narrative Review From Mechanisms to Clinical Management

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Vitamin D is an essential fat‐soluble nutrient primarily obtained through cutaneous synthesis triggered by ultraviolet exposure and dietary intake. After systemic metabolism and activation, it binds to vitamin D receptors widely distributed in the central and peripheral nervous systems, exerting pleiotropic neuroprotective and regulatory biological ...
Nan Zhao, Yang Yang, Wanqiu Yu, Yuhang Zhu, Zhaoqiong Zhu   +4 more
wiley   +1 more source

Maternal Vitamin D Deficiency is Associated With Sex‐Dependent Alterations in Neurodevelopment‐Related Gene Expression, Particularly in the Hypothalamus

Molecular Nutrition &Food Research, Volume 70, Issue 20, 28 October 2026.
Maternal vitamin D deficiency (VDD) affects early brain development in a sex‐dependent manner. VDD accelerates neuronal differentiation and synaptogenesis. Male offspring exhibit broader transcriptomic alterations, including dysregulation of melanocortin‐pathway and synaptic signaling genes, indicating greater vulnerability of hypothalamic circuits ...
Lidia Saidi, Emmanuel Snacel‐Fazy, Eva Seipelt, Nicole Haroun, Julien Astier, Charlène Couturier, Mohamed El Soltani, Eric Sérée, Flavie Sicard, Habib Hammou, Michel Puceat, Jean‐François Landrier, Lourdes Mounien   +12 more
wiley   +1 more source

Pro-Opiomelanocortin-Derived Peptides Induce 11-1 0 Production in Human Monocytes

, 1996
Bhardwaj R, Schwarz A, Becher E, et al. Pro-Opiomelanocortin-Derived Peptides Induce 11-1 0 Production in Human Monocytes. The Journal of Immunology.
Mahnke, Karsten, Bhardwaj, Ranjit, Becher, Eva ; https://orcid.org/, Schwarz, Thomas, Luger, Thomas, Schwarz, Agatha, Aragane, Yoshi   +6 more
core  

5-HT\(_{\text{2C}}\)Rs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis [PDF]

, 2008
Drugs activating 5-hydroxytryptamine 2C receptors (5-HT\(_{\text{2C}}\)Rs) potently suppress appetite, but the underlying mechanisms for these effects are not fully understood.
Heisler, Lora K., Xu, Yong, Williams, Kevin W., Lowell, Bradford, Elmquist, Joel K., Anderson, Jason G., Lowell, Bradford B., Choi, Michelle J., Zigman, Jeffrey M., Kohno, Daisuke, Lee, Charlotte E., Jones, Juli E.   +11 more
core   +1 more source

Acute ayahuasca administration attenuates binge‐like eating and anxiety‐related behaviors in mice subjected to intermittent fasting

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Human binge eating disorder is characterized by recurrent episodes of excessive food consumption accompanied by loss of control and is strongly associated with alterations in reward processing and emotional regulation. Ayahuasca, a psychoactive botanical preparation traditionally used in Amazonian medicine, has been shown to modulate ...
Cristian Ferreira Corona, Felipe Alves Alencar Lima, Jessica Sabrina Canedo da Silva Sumensse, Kevin Donansan Carvalho, Pedro Henrique Grignet, Heloisa Deola Confortim, Maria Claudia Gross, Fabiana Aidar Firmino, Fernanda Ferreira Evangelista, Francisney Pinto Nascimento, Jean Franciesco Vettorazzi   +10 more
wiley   +1 more source