Results 91 to 100 of about 16,494 (203)

Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers

Drug Design, Development and Therapy, 2016
Yi-fan Zhang,1 Xiao-jian Dai,1 Yong Yang,1 Xiao-yan Chen,1 Ting Wang,2 Yun-biao Tang,3 Cheng-yuan Tsai,4 Li-wen Chang,4 Yu-ting Chang,4 Da-fang Zhong1 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of ...
Zhang YF, Dai XJ, Yang Y, Chen XY, Wang T, Tang YB, Tsai CY, Chang LW, Chang YT, Zhong DF   +9 more
doaj  

Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold

Computational and Structural Biotechnology Journal
TRP channels are important pharmacological targets in physiopathology. TRPV2 plays distinct roles in cardiac and neuromuscular function, immunity, and metabolism, and is associated with pathologies like muscular dystrophy and cancer.
Èric Catalina-Hernández, Mario López-Martín, David Masnou-Sánchez, Marco Martins, Victor A. Lorenz-Fonfria, Francesc Jiménez-Altayó, Ute A. Hellmich, Hitoshi Inada, Antonio Alcaraz, Yuji Furutani, Alfons Nonell-Canals, Jose Luis Vázquez-Ibar, Carmen Domene, Rachelle Gaudet, Alex Perálvarez-Marín   +14 more
doaj   +1 more source

AKTIVITAS ANTIHIPERURIKEMIA EKSTRAK ETIL ASETAT DAN ETANOL BUAH SALAK VARIETAS BONGKOK (Salacca edulis Reinw.) PADA TIKUS GALUR WISTAR [Antihyperuricemic Activity of Ethyl Acetate and Ethanol Extracts of Snake Fruit var. Bongkok (Salacca edulis Reinw.) on Wistar Rat]

Jurnal Teknologi dan Industri Pangan, 2011
The aims of the study was to determine antihyperuricemic activity of ethyl acetate and ethanol extractsof snake fruit (Salacca edulis Reinw.) var. Bongkok on Wistar male rats.
Leni Herliani Afrianti1)*, Elin Yulinah Sukandar2), I Ketut Adnyana2), Slamet Ibrahim3)   +3 more
doaj  

Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis

Pediatric Cardiology, 2020
Jack Rubinstein, Jessica G. Woo, Anastacia M. Garcia, T. Alsaied, Jia Li, P. Lunde, Ryan A. Moore, M. Laasmaa, A. Sammons, W. Mays, S. Miyamoto, W. Louch, G. Veldtman   +12 more
semanticscholar   +1 more source

Structural basis for the modulation of MRP2 activity by phosphorylation and drugs

Nature Communications
Multidrug resistance-associated protein 2 (MRP2/ABCC2) is a polyspecific efflux transporter of organic anions expressed in hepatocyte canalicular membranes.
Tiziano Mazza, Theodoros I. Roumeliotis, Elena Garitta, David Drew, S. Tamir Rashid, Cesare Indiveri, Jyoti S. Choudhary, Kenneth J. Linton, Konstantinos Beis   +8 more
doaj   +1 more source

Probenecid [PDF]

, 2020
openaire   +1 more source

Pannexins in the heart: cell-specific expression and contributions to disease. [PDF]

Cell Tissue Res
Renton MC, Sedovy MW, Reynolds A, Hoch A, Roberts K, Sarmiento R, Toler C, Johnstone SR.   +7 more
europepmc   +1 more source

Reining in Multidrug Resistance Protein 1 via Binding Its Flexible Interdomain Linker with Sequence-Selective Peptide-Binding Nanoparticles. [PDF]

Biomacromolecules
Ghosh A, Sharma M, Zhao Y.
europepmc   +1 more source

Serine encodes drug selectivity in human OAT1. [PDF]

Structure
Dai Y, Lee CH.
europepmc   +1 more source

Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine

Xenobiotica; the fate of foreign compounds in biological systems, 2017
Fanuel T. Hagos, M. Daood, Jacob A Ocque, T. Nolin, H. Bayır, S. Poloyac, P. Kochanek, R. Clark, P. Empey   +8 more
semanticscholar   +1 more source