Results 61 to 70 of about 909,831 (225)

Probing gravitation with pulsars

open access: yes, 2012
Radio pulsars are fascinating and extremely useful objects. Despite our on-going difficulties in understanding the details of their emission physics, they can be used as precise cosmic clocks in a wide-range of experiments -- in particular for probing ...
Kramer, Michael
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Particle-Stabilized Fluid-Fluid Interfaces: The Impact of Core Composition on Interfacial Structure

open access: yesFrontiers in Chemistry, 2018
The encapsulation of small molecule drugs in nanomaterials has become an increasingly popular approach to the delivery of therapeutics. The use of emulsions as templates for the synthesis of drug impregnated nanomaterials is an exciting area of research,
Alison Tasker   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Comparative Study Of Probing Done with and without Endoscopic Assistance

open access: yesDelhi Journal of Ophthalmology, 2015
Aims: The aims of our study were (1) to compare success of probing done blindly and probing done under endoscopic assistance (2) to correlate the findings of blind probing with endoscopic examination findings.
Ishan Acharya   +2 more
doaj   +1 more source

A better Metaphor for Understanding Consciousness? [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2015
The article is an attempt at – yet once again – finding a source of more fitting metaphor for the study of consciousness inside the framework of quantum mechanics. It starts by doubting into the possibility of the naturalization of research of experience.
Uban Kordes
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Relationship between Mode of Delivery and Frequency and Treatment Outcomes of Congenital Nasolacrimal Dacryostenosis

open access: yesİstanbul Medical Journal, 2021
Introduction:The present study evaluates the relationship between the mode of delivery and the frequency and treatment outcomes of congenital nasolacrimal duct obstruction (CNDO).Methods:The medical records of children who were referred to oculoplasty ...
Fatma Esin Özdemir   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research on cyberspace surveying and mapping technology

open access: yes网络与信息安全学报, 2016
Cyberspace surveying and mapping technology is a network common foundation and application technology.The research progress of cyberspace surveying and mapping technology was reviewed and discussed.Firstly,the con-notation and principle framework of ...
Fan ZHAO,Xiang-yang LUO,Fen-lin LIU
doaj   +1 more source

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