Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
PROBING POTENTIAL OUTPUT: MONETARY POLICY, CREDIBILITY AND OPTIMAL LEARNING UNDER UNCERTAINTY [PDF]
The effective conduct of monetary policy is hampered by uncertainty surrounding the level of potential output. Here, the case for following a more aggressive policy to learn about the economy is considered in a model where potential output is changing ...
James Yetman
core
Bacterial metabolism of methylated amines and identification of novel methylotrophs in Movile Cave [PDF]
Movile Cave, Romania, is an unusual underground ecosystem that has been sealed off from the outside world for several million years and is sustained by non-phototrophic carbon fixation. Methane and sulfur-oxidising bacteria are the main primary producers,
Alexandra M Hillebrand-Voiculescu +20 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Probing of congenital nasolacrimal duct obstruction with dacryoendoscope
Kumiko Kato, Koichi Matsunaga, Yuko Takashima, Mineo KondoDepartment of Ophthalmology Mie University School of Medicine, Tsu, JapanBackground: A congenital nasolacrimal duct obstruction (CNLDO) is a relatively common disease in infants.
Kato K +3 more
core
Analyzing the functionality of the human intestinal microbiota by stable isotope probing [PDF]
Key words: gut bacteria, dietary carbohydrates, digestion, RNA-SIP, TIM-2, HITChip, human trial The human gastro-intestinal (GI) tract comprises a series of complex and dynamic organs ranging from the stomach to the distal colon, which harbor immense ...
Kovatcheva, P.P.
core
Evaluation and Treatment of Congenital Nasolacrimal Duct Obstruction
Congenital nasolacrimal duct obstruction is a common problem in neonates that results in epiphora, superimposed infection and amblyopia. Our aim is to review causes and current management of this problem in pediatric population.
Gamze Öztürk Karabulut, Korhan Fazil
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
For decades, probing clinical pocket depth and attachment level have been recognized as the dentist's most important tools in diagnosing periodontal health and disease. They are physical methods to measure the distance from the bottom of a pocket to a reference line, usually the gingival margin or the cemento-enamel junction.
openaire +2 more sources
Endoscopic-guided probing for the management of congenital nasolacrimal duct obstruction
Purpose This study aimed to assess the value of direct visualization during probing of congenital nasolacrimal duct obstruction using nasal endoscopy and its effect on the success rate.
Ayman E Abd El Ghafar
doaj +1 more source

