Results 91 to 100 of about 387,004 (310)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Primary probing for congenital nasolacrimal duct obstruction with manually curved Bowman probes
, 2013 Didem Serin,1 Ibrahim Bulent Buttanri,1 Mehmet Sahin Sevim,1 Bahtinur Buttanri21Eye Clinic, Haydarpasa Numune Education and Research Hospital, 2Eye Clinic, Sisli Etfal Education and Research Hospital, Istanbul, TurkeyPurpose: To evaluate the effect of ...
Sevim MS +3 more
core
Indian Journal of Ophthalmology, 2015 Purpose: To investigate outcomes for different treatment modalities in congenital nasolacrimal duct obstruction (CNLDO) in an Indian population. Design: Retrospective, interventional, case series.
Sahil Bhandari +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Performance Evaluation of Quadratic Probing and Random Probing Algorithms in modeling Hashing Technique [PDF]
, 2022 In hashing technique, a hash table and hash map represent a data structure for a group of objects to map between key and value pairs, as the hash table is affected by collision and overflow.
Alhammadi, Nafea Ali Majeed +1 more
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 2016 Emad Abdelaal Elsawaby, Rania Asem El Essawy, Sameh Hassan Abdelbaky, Yomna Magdy Ismail Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt Purpose: Evaluation of efficiency, complications, and advantages of pushed ...
Elsawaby EA +3 more
core
Probing the arrangement of hyperplanes [PDF]
, 1995 In this paper we investigate the combinatorial complexity of an algorithm to determine the geometry and the topology related to an arrangement of hyperplanes in multi-dimensional Euclidean space from the “probing” on the arrangement.
Aoki, Yasukazu
core +1 more source
Reproducibility of Periodontal Probing [PDF]
, 1993 This study evaluated reproducibility of periodontal probing by conventional manual and automated force-controlled electronic probes. A total of 1206 sites (6 sites per tooth including maxillary and mandibular incisor/canine, premolar, and molar sites) in
Wang, Su-Fang
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source