Results 81 to 90 of about 1,227,464 (275)

Probing Pseudogap by Josephson Tunneling

open access: yes, 2000
We propose here an experiment aimed to determine whether there are superconducting pairing fluctuations in the pseudogap regime of the high-$T_c$ materials. In the experimental setup, two samples above $T_c$ are brought into contact at a single point and
A. I. Larkin   +12 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Measurement Accuracy Investigation of Touch Trigger Probe with Five-Axis Machine Tools

open access: yesArchive of Mechanical Engineering, 2016
The touch trigger probe plays an important role in modern metrology because of its robust and compact design with crash protection, long life and excellent repeatability.
Rahman Md. Mizanur, Mayer J.R.R.
doaj   +1 more source

First-principles modelling for time-resolved ARPES under different pump–probe conditions [PDF]

open access: green, 2021
Umberto De Giovannini   +3 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Comparative Study Of Probing Done with and without Endoscopic Assistance

open access: yesDelhi Journal of Ophthalmology, 2015
Aims: The aims of our study were (1) to compare success of probing done blindly and probing done under endoscopic assistance (2) to correlate the findings of blind probing with endoscopic examination findings.
Ishan Acharya   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The Effectiveness of Probing for the Treatment of Congenital Nasolacrimal Duct Obstruction

open access: yesTürk Oftalmoloji Dergisi, 2012
Pur po se: To investigate the outcome of probing in patients with congenital nasolacrimal duct obstruction and to evaluate the success rate among age groups.
Ebru Esen   +4 more
doaj   +1 more source

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