Results 51 to 60 of about 2,120 (141)

Genomic Insights and Matrilineal Evolution Reveal Potential Dispersal Patterns of Chitala Species (Osteoglossomorpha: Notopteridae) in the Sundaland Biodiversity Hotspot

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
This study reports the first complete mitochondrial genome of Chitala borneensis and the re‐sequencing of Chitala lopis from Sundaland. Analyses of genetic structure, matrilineal phylogenies, and TimeTree‐based divergence estimates elucidate the evolutionary history and dispersal dynamics of extant Chitala species.
Flandrianto Sih Palimirmo   +13 more
wiley   +1 more source

An Integrated Framework for AI Assisted Level Design in 2D Platformers

open access: yes, 2018
The design of video game levels is a complex and critical task. Levels need to elicit fun and challenge while avoiding frustration at all costs. In this paper, we present a framework to assist designers in the creation of levels for 2D platformers.
Aramini, Antonio Umberto   +2 more
core   +1 more source

Conserved Gene Order and Adaptive Evolution in Mitochondrial Genomes of Calappa Crabs: Insights Into Ecological Specialization and Phylogenetic Utility

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
This study presents the first complete mitochondrial genomes of five Calappa species, filling a critical gap in genomic resources for the family Calappidae. Our analyses confirm the monophyly of Calappidae, detect positive selection in key energy metabolism genes (ATP6, ND2, ND5), and reveal conserved gene arrangement patterns.
Zhengfei Wang   +7 more
wiley   +1 more source

CRISPR gene editing of AtRING1 unravels a critical role of RAWUL domain in PRC1 repression of transcription

open access: yesThe Plant Journal, Volume 125, Issue 6, March 2026.
SUMMARY Polycomb Group (PcG) proteins, including members of Polycomb Repressive Complex 1 and 2 (PRC1 and PRC2), regulate many key developmental processes through transcriptional gene repression. While the molecular mechanisms of PRC2 and its histone methyltransferase involved in depositing histone 3 lysine 27 trimethylation (H3K27me3) are well ...
Qiannan Wang   +3 more
wiley   +1 more source

Systematic Literature Review of Meta-heuristic Algorithms and their Application in Procedural Content Generation (PCG) in the Context of Computer Games

open access: yes
Abstract This study investigated the use of metaheuristics and algorithms inspired by nat- ural processes to determine optimal solutions for procedural content generation (PCG) for the automatic creation of video game content. A systematic review of studies published between 2007 and 2023 was conducted to analyze the use of metaheuristics in ...
Sana Alyaseri, Roopak Sinha, Parma Nand
openaire   +1 more source

Automated Game Design Learning

open access: yes, 2017
While general game playing is an active field of research, the learning of game design has tended to be either a secondary goal of such research or it has been solely the domain of humans.
Mateas, Michael   +2 more
core   +1 more source

From Trend Analysis to Virtual World System Design Requirement Satisfaction Study

open access: yes, 2020
Virtual worlds have become global platforms connecting millions of people and containing various technologies. The development of technology, shift of market value, and change of user preference shape the features of virtual worlds.
Cai, Hongming   +5 more
core   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 7, 16 February 2026.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae   +9 more
wiley   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

open access: yesAdvanced Materials, Volume 38, Issue 9, 12 February 2026.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng   +9 more
wiley   +1 more source

Modern Trends in the Automatic Generation of Content for Video Games [PDF]

open access: yes, 2016
Attractive and realistic content has always played a crucial role in the penetration and popularity of digital games, virtual environments, and other multimedia applications.
Bontchev, Boyan
core  

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