Results 101 to 110 of about 2,908,953 (289)

Representations for the Procedural Content Generation of Puzzle Game Instances: A Systematic Literature Review

IEEE Access
Procedural Content Generation (PCG) is the use of automatic techniques to create content for games, varying from the generation of fundamental units such as textures or sound to complex environments and entire games.
Jose A. del Solar-Zavala, Nicolas A. Barriga   +1 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Retaliation as a response to procedural unfairness: a self-regulatory approach

, 2008
When does procedural unfairness result in retaliation, and why do recipients of unfair treatment sometimes pursue and other times inhibit retaliation? Five studies addressed these questions.
Sedikides, Constantine, Sedikides, C., De Cremer, David, Brebels, L.G.G., Constantine Sedikides, De Cremer, D (David), Brebels, Lieven, Lieven Brebels, Brebels, LGG, David De Cremer, Sedikides, C, De Cremer, D.   +11 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Generalized Group Testing Procedures

The Annals of Statistics, 1977
A person wishes to determine which, if any, of $n = \Pi^k_{j=1} a_j$ i.i.d. random variables, $X(i_1,\cdots, i_k), i_j = 1,\cdots, a_j$, lie in some specified set $A$. Such observations will be called unsafe. It is assumed that the density of the $X$'s is known and that $Y_j(i_1,\cdots, i_j)$, the sum of all the $X$'s whose first $j$ indices are $i_1 ...
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

AI-directed procedural content generation for personalized XR in industrial-heritage museums

Frontiers in Virtual Reality
This paper introduces an AI-directed procedural content generation (PCG) framework for Extended Reality (XR), implemented as a rule-based expert system with probabilistic scoring, and describes its use in an industrial heritage museum.
Başak Çakmak, Başak Çakmak, Aslı Çekmiş   +2 more
doaj   +1 more source

Efficient Procedural Generation of Forests.

J. WSCG, 2014
Forested landscapes are an important component of many large virtual environments in games and film. In order to reduce modelling time, procedural methods are often used. Unfortunately, procedural tree generation tends to be slow and resource-intensive for large forests.
Kenwood, Julian, Gain, James, Marais, Patrick   +2 more
openaire   +2 more sources