Results 81 to 90 of about 322,791 (290)

Enhancing 3D Printing with Procedural Generation and STL Formatting Using Python

open access: yesApplied Sciences
Three-dimensional printing has become a fast-growing industry. The first phase of this technology is the design of a 3D object to personalize it and optimize its production. This paper explores the procedural generation of the 3D model.
Jakub Kopowski   +3 more
doaj   +1 more source

Music-Based Procedural Content Generation for Games [PDF]

open access: yes, 2015
A geração procedimental é algo ainda recente no mundo académico, que se entende como a criação de conteúdos automaticamente via algoritmos. Há várias razões para o desenvolvimento desta técnica, mas a principal é a redução da memória consumida, pois os ...
Nuno Filipe Bernardino Oliveira
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Procedurally Generated City [PDF]

open access: yes, 2011
Bakalářská práce se zabývá procedurálním generováním měst. Prozkoumává již existující systémy a zabývá se používanými algoritmy a postupy v této oblasti.
Pazdera, Radek
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Procedural generation of aesthetic patterns from dynamics and iteration processes

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2017
Aesthetic patterns are widely used nowadays, e.g., in jewellery design, carpet design, as textures and patterns on wallpapers, etc. Most of the work during the design stage is carried out by a designer manually.
Gdawiec Krzysztof
doaj   +1 more source

Modern Trends in the Automatic Generation of Content for Video Games [PDF]

open access: yes, 2016
Attractive and realistic content has always played a crucial role in the penetration and popularity of digital games, virtual environments, and other multimedia applications.
Bontchev, Boyan
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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