Results 141 to 150 of about 30,537,982 (365)

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Weather forecast for simulation models of agroecosystem production

Lietuvos Matematikos Rinkinys, 1998
The forecast of the agroecosystem fate including the rate of crop development and expected yield are considered as the basic tasks of the dynamic agroecological modelling system that has been developed at the University of Klaipėda. This paper describes
Eugenija Žiniauskaitė, Vitalijus Denisovas   +1 more
doaj   +1 more source

Pion Production fromπ−−pCollisions in the Long-Range Interaction Model [PDF]

, 1960
Freda Salzman, George Salzman
openalex   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Particle production in 6.2 GeV p-p collisions treated by a statistical model [PDF]

, 1960
R. Hagedory
openalex   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Analysis Of The Pressure Behavior Of A Production Well Subject To Interference And Its Application To Reservoir Models [PDF]

, 1965
R. Thomere, Katie Arthur
openalex   +2 more sources

Editorial: Irradiation technologies for vaccine development

Frontiers in Immunology, 2023
Viskam Wijewardana, Sebastian Ulbert, Giovanni Cattoli   +2 more
doaj   +1 more source

Production Model Press for the Preparation of Bacterial Cell Walls [PDF]

, 1962
T. D. Perrine, E. Ribi, W. Maki, B. Miller, E. Oertli   +4 more
openalex   +1 more source

On production costs in vertical differentiation models [PDF]

In this paper, we analyse the effects of the introduction of a unit production cost beside a fixed cost of quality improvement in a duopoly model of vertical product differentiation.
Dorothée Brécard
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