Results 31 to 40 of about 4,556 (199)

A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. [PDF]

open access: yes, 2015
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in ...
Blasio, Angelo   +13 more
core   +2 more sources

Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]

open access: yes, 2020
Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core   +1 more source

Input–output connections of LJA5 prodynorphin neurons

open access: yesJournal of Comparative Neurology, 2020
Abstract Sensory information is transmitted from peripheral nerves, through the spinal cord, and up to the brain. Sensory information may be modulated by projections from the brain to the spinal cord, but the neural substrates for top‐down sensory control are incompletely understood.
Lindsay J. Agostinelli   +4 more
openaire   +2 more sources

Pathological alterations in striatal compartments in the human brain of autism spectrum disorder

open access: yesMolecular Brain, 2020
The striatum comprises a mosaic structure of striosomal and matrix compartments. Imbalanced neuronal activity between striosomes and matrix is implicated in neurological deficits in psychomotor and limbic functions.
Hsiao-Ying Kuo, Fu-Chin Liu
doaj   +1 more source

A role for transcriptional repressor methyl-CpG-binding protein 2 and plasticity-related gene serum- and glucocorticoid-inducible kinase 1 in the induction of inflammatory pain states [PDF]

open access: yes, 2007
Activity-dependent changes in neurons of the rat superficial dorsal horn are crucial for the induction and maintenance of neuropathic and inflammatory pain states.
Geranton, SM   +2 more
core   +1 more source

Circulating phagocytes: The ancient and conserved interface between immune and neuroendocrine function [PDF]

open access: yes, 2017
Immune and neuroendocrine functions display significant overlap in highly divergent and evolutionarily distant models such as molluscs, crustaceans, insects and mammals.
MALAGOLI, Davide   +3 more
core   +1 more source

Dentate Gyrus [PDF]

open access: yes, 2008
This report contains a gene expression summary of the dentate gyrus (DG), derived from the Allen Brain Atlas (ABA) _in situ_ hybridization mouse data set.
Allen Institute for Brain Science   +3 more
core   +2 more sources

VARIABILITY OF PDYN AND OPRK1 GENES IN FOUR ARGENTINIAN POPULATIONS AND ITS GENETIC ASSOCIATION WITH CLINICAL VARIABLES RELATED TO ACUTE POSTSURGICAL PAIN [PDF]

open access: yesBAG. Journal of Basic and Applied Genetics, 2022
Several population studies showed an association between variation in pain sensitivity and genetic polymorphisms located in Prodynorphin (PDYN) and Kappa Opioid Receptor (OPRK1) human genes.
Di Santo Meztler G.P.   +5 more
doaj   +1 more source

Mouse models of surgical and neuropathic pain produce distinct functional alterations to prodynorphin expressing neurons in the prelimbic cortex

open access: yesNeurobiology of Pain, 2023
The medial prefrontal cortex (mPFC) consists of a heterogeneous population of neurons that respond to painful stimuli, and our understanding of how different pain models alter these specific mPFC cell types remains incomplete. A distinct subpopulation of
Shudi Zhou, Yuexi Yin, Patrick L. Sheets
doaj   +1 more source

Gut sensing of food ingredients and interoception-mediated regulation of feeding and glucose metabolism. [PDF]

open access: yesPhysiol Rep
Abstract Food intake not only provides pleasure through exteroceptive sensations such as taste and smell but also elicits beneficial physiological effects via interoceptive signals arising from the gastrointestinal tract and beyond. Among these interoceptive pathways, vagal sensory (vagal afferent) nerves play a central role in transmitting food ...
Iba K, Kitano R, Iwasaki Y.
europepmc   +2 more sources

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