A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. [PDF]
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in ...
Blasio, Angelo +13 more
core +2 more sources
Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]
Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core +1 more source
Input–output connections of
Abstract Sensory information is transmitted from peripheral nerves, through the spinal cord, and up to the brain. Sensory information may be modulated by projections from the brain to the spinal cord, but the neural substrates for top‐down sensory control are incompletely understood.
Lindsay J. Agostinelli +4 more
openaire +2 more sources
Pathological alterations in striatal compartments in the human brain of autism spectrum disorder
The striatum comprises a mosaic structure of striosomal and matrix compartments. Imbalanced neuronal activity between striosomes and matrix is implicated in neurological deficits in psychomotor and limbic functions.
Hsiao-Ying Kuo, Fu-Chin Liu
doaj +1 more source
A role for transcriptional repressor methyl-CpG-binding protein 2 and plasticity-related gene serum- and glucocorticoid-inducible kinase 1 in the induction of inflammatory pain states [PDF]
Activity-dependent changes in neurons of the rat superficial dorsal horn are crucial for the induction and maintenance of neuropathic and inflammatory pain states.
Geranton, SM +2 more
core +1 more source
Circulating phagocytes: The ancient and conserved interface between immune and neuroendocrine function [PDF]
Immune and neuroendocrine functions display significant overlap in highly divergent and evolutionarily distant models such as molluscs, crustaceans, insects and mammals.
MALAGOLI, Davide +3 more
core +1 more source
This report contains a gene expression summary of the dentate gyrus (DG), derived from the Allen Brain Atlas (ABA) _in situ_ hybridization mouse data set.
Allen Institute for Brain Science +3 more
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VARIABILITY OF PDYN AND OPRK1 GENES IN FOUR ARGENTINIAN POPULATIONS AND ITS GENETIC ASSOCIATION WITH CLINICAL VARIABLES RELATED TO ACUTE POSTSURGICAL PAIN [PDF]
Several population studies showed an association between variation in pain sensitivity and genetic polymorphisms located in Prodynorphin (PDYN) and Kappa Opioid Receptor (OPRK1) human genes.
Di Santo Meztler G.P. +5 more
doaj +1 more source
The medial prefrontal cortex (mPFC) consists of a heterogeneous population of neurons that respond to painful stimuli, and our understanding of how different pain models alter these specific mPFC cell types remains incomplete. A distinct subpopulation of
Shudi Zhou, Yuexi Yin, Patrick L. Sheets
doaj +1 more source
Gut sensing of food ingredients and interoception-mediated regulation of feeding and glucose metabolism. [PDF]
Abstract Food intake not only provides pleasure through exteroceptive sensations such as taste and smell but also elicits beneficial physiological effects via interoceptive signals arising from the gastrointestinal tract and beyond. Among these interoceptive pathways, vagal sensory (vagal afferent) nerves play a central role in transmitting food ...
Iba K, Kitano R, Iwasaki Y.
europepmc +2 more sources

