Establishment of a graphene quantum dot (GQD) based steroid binding assay for the nuclear progesterone receptor (pgr). [PDF]
Biochem Biophys RepPreviously, we established a homogeneous assay for membrane progesterone receptor alpha (mPRα) ligands by conjugating semiconductor nanoparticles known as graphene quantum dots (GQDs) to mPRα. When mixed with a progesterone-BSA-fluorescein isothiocyanate
Hossain MF +5 more
europepmc +2 more sources
Progesterone receptor expression declines in the guinea pig uterus during functional progesterone withdrawal and in response to prostaglandins. [PDF]
PLoS ONE, 2014 Progesterone withdrawal is essential for parturition, but the mechanism of this pivotal hormonal change is unclear in women and other mammals that give birth without a pre-labor drop in maternal progesterone levels.
Toni N Welsh +3 more
doaj +1 more source
Loss of progesterone receptor-mediated actions induce preterm cellular and structural remodeling of the cervix and premature birth. [PDF]
PLoS ONE, 2013 A decline in serum progesterone or antagonism of progesterone receptor function results in preterm labor and birth. Whether characteristics of premature remodeling of the cervix after antiprogestins or ovariectomy are similar to that at term was the ...
Steven M Yellon +5 more
doaj +1 more source
Cells, 2022 How progesterone influences ovarian follicle growth is a difficult question to answer because ovarian cells synthesize progesterone and express not only the classic nuclear progesterone receptor but also members of the progestin and adipoQ receptor ...
John J. Peluso
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Intestinal tumorigenesis is not affected by progesterone signaling in rodent models. [PDF]
PLoS ONE, 2011 Clinical data suggest that progestins have chemopreventive properties in the development of colorectal cancer. We set out to examine a potential protective effect of progestins and progesterone signaling on colon cancer development.
Jarom Heijmans +11 more
doaj +1 more source
The importance of simultaneous determination of breast cancer biomarkers [PDF]
Archive of Oncology, 2002 It is shown that steroid hormone receptors by themselves are not sufficiently strong prognostic factors in management of breast cancer. For that reason, simultaneous consideration of different biomarkers seems to be more appropriate for clinical use, i.e.
Markićević Milan +3 more
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The Effect of Imbalanced Progesterone Receptor-A/-B Ratio on Gelatinase Expressions in Endometriosis [PDF]
International Journal of Fertility and Sterility, 2019 Background Gelatinases degrade extracellular matrix (ECM) components to allow for physiological remodeling and contribute to pathological tissue destruction in endometriosis.
Sepideh Mousazadeh +4 more
doaj +1 more source
Pathological implication of progesterone receptor expression in patients diagnosed with meningioma [PDF]
Romanian Journal of NeurologyObjectives. To assess the progesterone receptor expression in meningioma patients and to characterize the histopathological and demographic features of them. Materials and methods.
Murooj Jassim Mohammed +3 more
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Estrogen and progesterone receptor expression in breast carcinoma
Journal of Pathology of Nepal, 2011 Background: Breast carcinoma is the most common malignancy diagnosed among women worldwide and second leading cause of cancer mortality. One of the hallmarks of the disease is expression of estrogen receptor and progesterone receptor that ultimately ...
TB Pathak +7 more
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Progestin receptor-mediated reduction of anxiety-like behavior in male rats. [PDF]
PLoS ONE, 2008 BACKGROUND: It is well known progesterone can have anxiolytic-like effects in animals in a number of different behavioral testing paradigms. Although progesterone is known to influence physiology and behavior by binding to classical intracellular ...
Catherine J Auger, Robin M Forbes-Lorman
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