Results 121 to 130 of about 2,512,088 (315)

Synthesis of the Abiraterone Derivatives 5α‐ and 5β‐Δ1‐Abiraterone and Structural Determination of an Unknown Metabolite in Human Serum Derived from Oral Abiraterone Acetate

ChemBioChem, EarlyView.
Abiraterone (Abi) acetate, a prostate cancer treatment, is orally administered and hydrolyzed, and multiple metabolites are produced in serum by various enzymes. Two novel Abi derivatives, 5α‐ and 5β‐Δ1‐abiraterone, are synthesized. Then, an unknown metabolite in serum is identified to be 5β‐Δ1‐abiraterone based on its extracted ion chromatogram ...
Noboru Hayama, Shizuyo Horiyama, Ryoma Okamoto, Yukina Nishi, Manae Yada, Ryuji Higashida, Jun Haginaka, Yoshihide Usami   +7 more
wiley   +1 more source

Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of 18F‐Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3

ChemMedChem, EarlyView.
Fluorinated peptidomimetics targeting muscarinic acetylcholine receptor subtype M3: Fluorinated peptidomimetic compounds based on a β‐alanine‐glycine scaffold, with lead compound 24 demonstrating high M3 selectivity and submicromolar potency. The first M3‐selective positron emission tomography radioligand, [18F]24, is synthesized and will be evaluated ...
Miguel A. Herrera‐Rueda, Maxwell A. Boateng, Melinda Wuest, Frederick G. West, Frank Wuest   +4 more
wiley   +1 more source

Characterization of the hormone responsive element involved in the regulation of the progesterone receptor gene. [PDF]

, 1991
J.-F. Savouret, A. Bailly, Micheline Misrahi, Claudine Rauch, Gérard Redeuilh, Anne Chauchereau, Edwin Milgröm   +6 more
openalex   +1 more source

Cytologic and Histologic Findings of Extrapleural Solitary Fibrous Tumor: Report of Two Cases

Diagnostic Cytopathology, EarlyView.
ABSTRACT Solitary fibrous tumors (SFT) are a rare neoplasm of mesenchymal origin. SFT was previously described primarily in the pleura and meninges; however, extrapleural and extra‐meningeal SFT have been reported in almost every anatomic site and account for up to 40% of cases.
Michael Tyler, Katsiaryna Khatskevich, Chadi Hajar, Jack Yang, Hao Liu   +4 more
wiley   +1 more source

Progesterone treatment shows greater protection in brain vs. retina in a rat model of middle cerebral artery occlusion: Progesterone receptor levels may play an important role

, 2016
Rachael S Allen, Iqbal Sayeed, Yuliya Oumarbaeva, Katherine C. Morrison, Paul Choi, Machelle T. Pardue, Donald G. Stein   +6 more
openalex   +2 more sources

Efficacy of the selective progesterone receptor agonist Nestorone for chronic experimental autoimmune encephalomyelitis [PDF]

, 2014
Laura Garay, Marı́a Claudia González Deniselle, Régine Sitruk‐Ware, Rachida Guennoun, Michaël Schumacher, Alejandro F. De Nicola   +5 more
openalex   +1 more source

Pleural Metastasis From Male Breast Cancer: A Case Report

Diagnostic Cytopathology, EarlyView.
ABSTRACT Male breast cancer (MBC) is a rare disease accounting for less than 1% of breast cancers and for 0.11% of all male malignancies. Despite the fact that the epidemiologic, clinical, and therapeutic literature regarding female breast cancer is well documented, little is known about the features of male breast cancer.
Patrizia Straccia, Esther Diana Rossi
wiley   +1 more source

Within‐Person Changes in Daily Ovarian Hormone Levels Influence Genetic Effects on Emotional Eating in Women

International Journal of Eating Disorders, EarlyView.
ABSTRACT Introduction Ovarian hormones (i.e., estradiol, progesterone) show robust phenotypic associations with binge eating and related behaviors (e.g., emotional eating) in females. Recent research suggests these associations may be due to ovarian hormone effects on genetic and environmental influences on dysregulated eating. However, no research has
Megan E. Mikhail, Kristen M. Culbert, Pamela K. Keel, S. Alexandra Burt, Cheryl L. Sisk, Alexander Johnson, Steven Boker, Micheal C. Neale, Kelly L. Klump   +8 more
wiley   +1 more source

Oxytocin Effects on Food Stimulus Processing and Food Intake in Females With or Without Binge Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating disorder (BED) is maintained by increased food‐related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight.
Julia Nannt, Mechteld M. van den Hoek Ostende, Brunna Tuschen‐Caffier, Markus Heinrichs, Daniel Sippel, Manfred Hallschmid, Jennifer Svaldi   +6 more
wiley   +1 more source

Steroid Receptor Coactivator 2 Is Critical for Progesterone-Dependent Uterine Function and Mammary Morphogenesis in the Mouse

, 2006
Atish Mukherjee, Selma M. Soyal, Rodrigo Fernandez‐Valdivia, Martine Géhin, Pierre Chambon, Francesco J. DeMayo, John P. Lydon, Bert W. O’Malley   +7 more
openalex   +1 more source