Results 31 to 40 of about 219,338 (264)
Медична наука України, 2017 Relevance. An important medical and social problem of modern obstetrics is threatening abortion. Among all threatened abortion risk factors today a special attention is given to genetic factors, in particular, to progesterone receptor gene polymorphism ...
O.S. Kryvopustov
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Placental weight and mortality in premenopausal breast cancer by tumor characteristics [PDF]
, 2013 Placental weight may be regarded as an indirect marker of hormone exposures during pregnancy. There is epidemiological evidence that breast cancer mortality in premenopausal women increases with placental weight in the most recent pregnancy.
Adolfsson, J. +6 more
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Cancer Reports, 2022 Background Hormone Receptor (HR)‐discordance between primary breast cancer and metastasis is a known biological phenomenon. Discordance studies usually comprise a heterogeneous group of HR‐positive and negative patients and allow for the comparison of ...
Sirus Djahansouzi +4 more
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Gynaecological uses of a new class of steroids: the selective progesterone receptor modulators [PDF]
, 2009 Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on various progesterone target tissues in vivo.
Chabbert-Buffet, N. +2 more
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Scientific Reports, 2017 Progesterone can block the oestradiol-induced GnRH/LH surge and inhibit LH pulse frequency. Recent studies reported that progesterone prevented premature LH surges during ovarian hyperstimulation in women. As the most potent stimulator of GnRH/LH release,
Wen He +8 more
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Estrogen and Progesterone Receptors in the Endometrium
Annals of the New York Academy of Sciences, 1997 The endometrium, as a target of estrogens and progestins, possesses the respective receptor proteins. These receptors belong to the superfamily of nuclear receptors, having important functional domains required for steroid ligand binding, for dimer formation, for interaction with HREs of DNA, for transcription modulation, for association with other ...
Moutsatsou, P., Sekeris, Constantine E.
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Synthetic epoxy-pregnan steroids: effects on anxiety behavior in rats [PDF]
, 2016 Neurosteroids like 3α-OH-5α-pregnan-20-one (allopregnanolone) and 3α-OH-5β-pregnan-20-one (pregnanolone) modulate the γ-aminobutyric acid-A (GABAA) receptor function and produce several effects that can be considered for therapeutical pruposes like ...
Coirini, Hector +2 more
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Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]
, 2010 Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B. +3 more
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Progesterone differentially affects the transcriptomic profiles of cow endometrial cell types
BMC Genomics, 2022 Background The endometrium is a heterogeneous tissue composed of luminal epithelial (LE), glandular epithelial (GE), and stromal cells (ST), experiencing progesterone regulated dynamic changes during the estrous cycle.
Gonçalo Pereira +6 more
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AIMS Molecular Science, 2021 Genetic predisposition has been suggested to play a role in the pathogenesis of endometriosis. The most common pathogenetic hypotheses is that there is possible dysregulation of the ligand-receptorial signaling involving the main sex hormones, eostrogen ...
Irene M. Waita +6 more
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