Results 31 to 40 of about 2,591,762 (410)

New insights into progesterone receptor signaling in the endometrium required for embryo implantation.

open access: yesJournal of Molecular Endocrinology, 2019
Progesterone's ability to maintain pregnancy in eutherian mammals highlighted this steroid as the "hormone of pregnancy". It was the unique "pro-gestational" bioactivity of progesterone that enabled eventual purification of this ovarian steroid to ...
F. DeMayo, J. Lydon
semanticscholar   +1 more source

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

open access: yes, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia   +4 more
core   +2 more sources

Efficacy of Fractional Laser on Steroid Receptors in GSM Patients

open access: yesBioengineering, 2023
Background: To compare the efficacy of CO2 fractional laser with that of topical estriol for treating genitourinary syndrome of menopause and to investigate the relationship between epithelial thickness and vaginal atrophy.
Stella Catunda Pinho   +9 more
doaj   +1 more source

Placental weight and mortality in premenopausal breast cancer by tumor characteristics [PDF]

open access: yes, 2013
Placental weight may be regarded as an indirect marker of hormone exposures during pregnancy. There is epidemiological evidence that breast cancer mortality in premenopausal women increases with placental weight in the most recent pregnancy.
Adolfsson, J.   +6 more
core   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

open access: yes, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E.   +6 more
core   +1 more source

PGR (progesterone receptor)

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
The progesterone receptor gene PGR is located on 11q22.1. The functional gene has 8 exons and 7 introns; the transcript is translated into 933 residues. The protein occurs as three isoforms viz. PR-A; PRB; PR-C and 11 splice variants.
G. Sherbet
semanticscholar   +1 more source

Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]

open access: yes, 2014
Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou   +28 more
core   +3 more sources

Selective progesterone receptor modulators (SPRMs): progesterone receptor action, mode of action on the endometrium and treatment options in gynecological therapies

open access: yesExpert opinion on therapeutic targets, 2016
Introduction: The progesterone receptor plays an essential role in uterine physiology and reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a valuable treatment option for hormone dependent conditions like uterine fibroids,
A. Wagenfeld   +3 more
semanticscholar   +1 more source

The Role of Progesterone Receptors in Breast Cancer

open access: yesDrug Design, Development and Therapy, 2022
The progesterone receptor (PR) modulates estrogen receptors α (ERα) action in breast cancer; it is an upregulated target gene of ER, and its expression is dependent on estrogen.
Zhuoying Li   +4 more
semanticscholar   +1 more source

Physiological Action of Progesterone in the Nonhuman Primate Oviduct

open access: yesCells, 2022
Therapies that target progesterone action hold potential as contraceptives and in managing gynecological disorders. Recent literature reviews describe the role of steroid hormones in regulating the mammalian oviduct and document that estrogen is required
Ov D. Slayden   +2 more
doaj   +1 more source

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