The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia+9 more
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Steroid Receptors and Vertebrate Evolution
Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago.
Baker, Michael E.
core
The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer. [PDF]
Summary In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical analysis was possible in 91.5% of the patients (75/82). Staining was evaluated using
Berger U+13 more
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Background Adaptive responses in fungi result from the interaction of membrane receptors and extracellular ligands. Many different classes of receptors have been described in eukaryotic cells. Recently a new family of receptors classified as belonging to
Gonzalez-Velazquez Waleska+2 more
doaj +1 more source
Family history of breast and ovarian cancer and triple negative subtype in hispanic/latina women. [PDF]
Familial breast and ovarian cancer prevalence was assessed among 1150 women of Mexican descent enrolled in a case-only, binational breast cancer study. Logistic regression was conducted to compare odds of triple negative breast cancer (TNBC) to non-TNBC ...
Anderson, Kristin+13 more
core +2 more sources
Hormonal modulators of glial ABCA1 and apoE levels[S]
Apolipoprotein E (apoE) is the major lipid carrier in the central nervous system. As apoE plays a major role in the pathogenesis of Alzheimer disease (AD) and also mediates repair pathways after several forms of acute brain injury, modulating the ...
Jianjia Fan+9 more
doaj
Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization [PDF]
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright @ 2011 Spandidos Publications Ltd.A vital function of the human placenta is to produce steroid hormones such as ...
Foster, H+5 more
core +1 more source
Immunolocalization of progesterone receptors in binucleate trophoblast cells of the buffalo placenta (Bubalus bubalis) [PDF]
The binucleate trophoblast cells (CTBs) of the water buffalo placenta (Bubalus bubalis) were studied with emphasis on the presence of progesterone receptor.
Carlos Eduardo Ambrósio+4 more
doaj
Summary: Altered progesterone responsiveness leads to female infertility and cancer, but underlying mechanisms remain unclear. Mice with uterine-specific ablation of GATA binding protein 2 (Gata2) are infertile, showing failures in embryo implantation ...
Cory A. Rubel+12 more
doaj
Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands ...
Fabio Augusto Ito+4 more
doaj +1 more source