Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation
EMBO Molecular Medicine, 2021 Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists, progestins, and transiently increases breast cancer risk. How progesterone and progestins affect the breast epithelium is poorly understood because we lack adequate ...
Marie Shamseddin +14 more
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Progestins as Anticancer Drugs and Chemosensitizers, New Targets and Applications
Pharmaceutics, 2021 Progesterone and its synthetic analogues, progestins, participate in the regulation of cell differentiation, proliferation and cell cycle progression.
Tatiana A. Fedotcheva +2 more
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Possible Participation of Adenine Nucleotide Translocase ANT1 in the Cytotoxic Action of Progestins, Glucocorticoids, and Diclofenac on Tumor Cells [PDF]
Pharmaceutics, 2023 A comparative analysis of the cytostatic effects of progestins (gestobutanoyl, megestrol acetate, amol, dienogest, and medroxyprogesterone acetate), glucocorticoids (hydrocortisone, dexamethasone), and diclofenac on tumor cells was carried out in order ...
Darya Ulchenko +4 more
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Fecal Progestin Extraction and Analysis for Non-invasive Monitoring of Ovarian Cycle in Beef Cows [PDF]
Pakistan Veterinary Journal, 2012 The aims of the present study were to determine presence of immunoreactive progestins in feces, correlate fecal progestins with plasma progesterone (P4) concentrations and subsequently assess the role of fecal progestins in monitoring estrous cycle in ...
N. Yimer§, Y. Rosnina*, H. Wahid, M.M. Bukar, A. Malik, K.C. Yap, M. Fahmi, P. Ganesamurthi and A.A. Saharee
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Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women [PDF]
PharmaceuticalsBackground/Objectives: This study aims to assess the effects of combined hormonal contraceptives (CHCs) on bone metabolism markers. It primarily measures osteocalcin and additionally examines other bone health markers, seeking to determine their ...
Alice Tassi +7 more
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Estrogens, Progestins, and Headache
Pediatric Neurology Briefs, 1991 Approaches to the therapy of hormone-related headaches are reviewed from the Department of Neurology, Temple University School of Medicine and the Comprehensive Headache Center at Germantown Hospital, Philadelphia, PA, and the Reproductive Endocrine Unit,
J Gordon Millichap
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The endogenous hydrogen gas (H2) drives women’s health: a comment on “Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas” [PDF]
Frontiers in EndocrinologyShuangling Yang +10 more
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Foods, 2023 The residues of progestins in milk are significant risk factors for teenage acne and may cause hormone-dependent cancers in consumers, so the determination of these residues in milk is very important.
Yan Su +4 more
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Frontiers in Endocrinology, 2022 Progestins, synthetic compounds designed to mimic the activity of natural progesterone (P4), are used globally in menopausal hormone therapy. Although the older progestins medroxyprogesterone acetate (MPA) and norethisterone (NET) have been implicated in
Meghan S. Perkins +4 more
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Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids. [PDF]
PLoS ONE, 2016 Progestins used in contraception and hormone replacement therapy are synthetic compounds designed to mimic the actions of the natural hormone progesterone and are classed into four consecutive generations.
Renate Louw-du Toit +4 more
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