Results 1 to 10 of about 10,095 (164)

Progestins - a review of clinical application in gynecology [PDF]

open access: yesAnnals of Medicine
Aims Progestins are a group of substances with a wide range of applications. They are classified into pregnanes, estranes, and gonanes, and further divided into four generations based on their testosterone (TE) or progesterone (P4) origin.
Dominika Żyła   +5 more
doaj   +2 more sources

Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation

open access: yesEMBO Molecular Medicine, 2021
Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists, progestins, and transiently increases breast cancer risk. How progesterone and progestins affect the breast epithelium is poorly understood because we lack adequate ...
Marie Shamseddin   +2 more
exaly   +2 more sources

Progestins as Anticancer Drugs and Chemosensitizers, New Targets and Applications

open access: yesPharmaceutics, 2021
Progesterone and its synthetic analogues, progestins, participate in the regulation of cell differentiation, proliferation and cell cycle progression.
Tatiana A Fedotcheva
exaly   +3 more sources

Estrogens, Progestins, and Headache

open access: yesPediatric Neurology Briefs, 1991
Approaches to the therapy of hormone-related headaches are reviewed from the Department of Neurology, Temple University School of Medicine and the Comprehensive Headache Center at Germantown Hospital, Philadelphia, PA, and the Reproductive Endocrine Unit,
J Gordon Millichap
doaj   +3 more sources

Development of a Magnetic Molecularly Imprinted Microsphere-Based Signal Amplified Semi-Homogeneous Method for Multidetection of Five Progestins in Milk

open access: yesFoods, 2023
The residues of progestins in milk are significant risk factors for teenage acne and may cause hormone-dependent cancers in consumers, so the determination of these residues in milk is very important.
Yan Su   +4 more
doaj   +1 more source

Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids. [PDF]

open access: yesPLoS ONE, 2016
Progestins used in contraception and hormone replacement therapy are synthetic compounds designed to mimic the actions of the natural hormone progesterone and are classed into four consecutive generations.
Renate Louw-du Toit   +4 more
doaj   +1 more source

Upregulation of an estrogen receptor-regulated gene by first generation progestins requires both the progesterone receptor and estrogen receptor alpha

open access: yesFrontiers in Endocrinology, 2022
Progestins, synthetic compounds designed to mimic the activity of natural progesterone (P4), are used globally in menopausal hormone therapy. Although the older progestins medroxyprogesterone acetate (MPA) and norethisterone (NET) have been implicated in
Meghan S. Perkins   +4 more
doaj   +1 more source

Possible Participation of Adenine Nucleotide Translocase ANT1 in the Cytotoxic Action of Progestins, Glucocorticoids, and Diclofenac on Tumor Cells

open access: yesPharmaceutics, 2023
A comparative analysis of the cytostatic effects of progestins (gestobutanoyl, megestrol acetate, amol, dienogest, and medroxyprogesterone acetate), glucocorticoids (hydrocortisone, dexamethasone), and diclofenac on tumor cells was carried out in order ...
Darya Ulchenko   +4 more
doaj   +1 more source

Effects of oral contraceptives on metabolic parameters in adult premenopausal women: a meta-analysis

open access: yesEndocrine Connections, 2020
Objective: To estimate the effect of oral contraceptives (OC) containing di fferent progestins on parameters of lipid and carbohydrate metabolism through a systematic review and meta-analysis. Patients and methods: Premenopausal women aged 18 or older,
Lina S Silva-Bermudez   +6 more
doaj   +1 more source

Therapeutic options of endometrial hyperplasia management. Current recommendations and prospective directions of treatment

open access: yesРепродуктивная эндокринология, 2021
Endometrial hyperplasia (EH) is a pathological condition characterized by proliferation of the endometrial glands with an increase in the glands/stroma ratio compared to normal proliferative endometrium. EH is a precursor to the development of one of the
T.F. Tatarchuk   +5 more
doaj   +1 more source

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