Long-Acting Reversible Contraception [PDF]
Unwanted pregnancy is a major public health problem both in developed and developing countries. Although the reduction in the rates of these pregnancies requires multifactorial approaches, increasing access to long-acting contraceptive methods can ...
Rogerio Bonassi Machado+8 more
doaj +1 more source
The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia+9 more
core +1 more source
The role of progestins in breast tissue is less well defined than in the endometrium. Although in vitro studies have shown that progestins induce a similar decrease in both estrogen and progesterone receptors and an increase in 17beta-estradiol dehydrogenase in the breast as in the endometrium, epidemiologic studies have suggested that progestins ...
G. Plu-Bureau, R. Sitruk-Ware
openaire +2 more sources
Medical treatment of adenomyosis: a literature review
Adenomyosis is a heterogeneous gynecologic disease with a range of clinical presentations, the most common being heavy menstrual bleeding and dysmenorrhea.
Vitaly B. Tskhay+2 more
doaj +1 more source
Response to Birrell SN: Commentary on "Photosensitizing Drugs and Risk of Skin Cancer in Women". [PDF]
Photodermatology, Photoimmunology &Photomedicine, Volume 41, Issue 4, July 2025.
Nielsen K+4 more
europepmc +2 more sources
Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus+6 more
core +1 more source
Progestin potency – Assessment and relevance to choice of oral contraceptives
Objectives: To evaluate current information on the potency of older and newer progestins and the relevance to oral contraceptive (OC) use. Methods: A medline search back to the last review (1985) was conducted.
Norman Goldstuck
doaj +1 more source
Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal+46 more
core +1 more source
Hormone Replacement Therapy (HRT): Utilisation Rates, Determinants and Impact on Health-Related Quality of Life in a Multi-Ethnic Asian Population [PDF]
Introduction: Hormone Replacement Therapy (HRT) is widely prescribed to provide relief from unpleasant climacteric symptoms, however for several decades, the benefits and risks of HRT have been debated.
BaoLin Pauline Soh+7 more
doaj +1 more source
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna+8 more
core +1 more source