Results 81 to 90 of about 399,116 (301)

Renal Tumors [PDF]

open access: yesAmerican Journal of Surgical Pathology, 2013
The International Society of Urological Pathology convened a consensus conference on renal cancer, preceded by an online survey, to address issues relating to the diagnosis and reporting of renal neoplasia. In this report, the role of biomarkers in the diagnosis and assessment of prognosis of renal tumors is addressed. In particular we focused upon the
Tan, Puay Hoon   +13 more
openaire   +4 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Predictive and prognostic cancer biomarkers revisited [PDF]

open access: yesExpert Review of Molecular Diagnostics, 2015
While both prognostic and predictive cancer biomarkers predict clinical outcome, the term 'predictive biomarker' is reserved for the association of a specific therapy with a specific clinical outcome. The advent of genomic signatures and next generation sequencing as candidate predictive biomarkers has led to lengthy and expensive processes for ...
openaire   +2 more sources

Response to “prognostic biomarkers in oral leukoplakia” [PDF]

open access: yesOral Diseases, 2019
We thank Professor Warnakulasuriya for his letter (Warnakulasuriya, 2019) and comments in relation to our systematic review of prospective studies assessing the prognostic biomarkers of oral leukoplakia (Villa et al., 2019). We agree that identifying prognostic biomarkers for oral leukoplakia is an important topic for oral medicine specialists.
Alessandro Villa   +9 more
openaire   +4 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Expression of Concern: T‐LAK cell‐originated protein kinase (TOPK): an emerging prognostic biomarker and therapeutic target in osteosarcoma

open access: yesMolecular Oncology, 2021
T‐lymphokine‐activated killer (T‐LAK) cell‐originated protein kinase (TOPK) is an emerging target with critical roles in various cancers; however, its expression and function in osteosarcoma remain unexplored.
Pichaya Thanindratarn   +7 more
doaj   +1 more source

Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection. [PDF]

open access: yes, 2016
Novel biomarkers and non-invasive diagnostic methods are urgently needed for the screening of gastric cancer to reduce its high mortality. We employed quantitative proteomics approach to develop discriminatory biomarker signatures from human saliva for ...
Cao, Cheng-Xi   +9 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Non‐invasive prognostic protein biomarker signatures associated with colorectal cancer

open access: yesEMBO Molecular Medicine, 2015
The current management of colorectal cancer (CRC) would greatly benefit from non‐invasive prognostic biomarkers indicative of clinicopathological tumor characteristics.
Silvia Surinova   +7 more
doaj   +1 more source

EPMA position paper in cancer:current overview and future perspectives [PDF]

open access: yes, 2015
At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive, and personalized medicine (PPPM). Individual patients will participate in more aspects of their healthcare.
Bubnov, Rostylav   +7 more
core   +5 more sources

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