Biomolecules, 2021 L-proline (proline) is a key regulator of embryogenesis, placental development, and fetal growth. However, the underlying mechanisms that support the beneficial effects of proline are largely unknown.
Ning Liu +7 more
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Current Plant Biology, 2023 Proline/P5C cycle between mitochondria and cytosol, play important roles in energy supply and ROS (Reactive oxygen species) generation in mammalian cell.
Wenhan Ying +6 more
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The sodium/proline transporter PutP of Helicobacter pylori. [PDF]
PLoS ONE, 2013 Helicobacter pylori is cause of chronic gastritis, duodenal ulcer and gastric carcinoma in humans. L-proline is a preferred energy source of the microaerophilic bacterium. Previous analyses revealed that HpputP and HpputA, the genes that are predicted to
Araceli Rivera-Ordaz +8 more
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Structure-activity relationships of fluorene compounds inhibiting HCV variants [PDF]
, 2020 Approximately 71 million people suffer from hepatitis C virus (HCV) infection worldwide. Persistent HCV infection causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma, resulting in approximately 400,000 deaths ...
Gadhe, Changdev G. +10 more
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Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome. [PDF]
PLoS ONE, 2013 Proline is an anomalous amino acid. Its nitrogen atom is covalently locked within a ring, thus it is the only proteinogenic amino acid with a constrained phi angle.
Alexander A Morgan, Edward Rubenstein
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Enzymatic production of trans‐4‐hydroxy‐l‐proline by proline 4‐hydroxylase
Microbial Biotechnology, 2021 Summary Trans‐4‐hydroxy‐l‐proline (Hyp) is a useful chiral building block for production of many nutritional supplements and pharmaceuticals. However, it is still challenging for industrial production of Hyp due to heavy environmental pollution and low ...
Xiulai Chen +4 more
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Proline transporters ProT and PutP are required for Staphylococcus aureus infection.
PLoS Pathogens, 2023 Proline acquired via specific transporters can serve as a proteinogenic substrate, carbon and nitrogen source, or osmolyte. Previous reports have documented that Staphylococcus aureus, a major community and nosocomial pathogen, encodes at least four ...
McKenzie K Lehman +5 more
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Proline Transport and Growth Changes in Proline Transport Mutants of Staphylococcus aureus
Microorganisms, 2022 Staphylococcus aureus is a major cause of skin/soft tissue infections and more serious infections in humans. The species usually requires the importation of proline to be able to survive. Previous work has shown that single mutations in genes that encode
William R. Schwan
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Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site [PDF]
, 2002 Background: Profilin is a small cytoskeletal protein which interacts with actin, proline-rich proteins and phosphatidylinositol 4,5-bisphosphate (PI(4,5)-P-2).
Ampe, Christophe +4 more
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Self-assembly, nematic phase formation and organocatalytic behaviour of a proline-functionalized lipopeptide [PDF]
, 2020 The self-assembly of the amphiphilic lipopeptide PAEPKI-C16 (P = proline, A = alanine, E = glutamic acid, K = lysine, I = isoleucine, C16 = hexadecyl) was investigated using a combination of spectroscopic, microscopic and scattering methods and compared ...
Aguilar, Andrea M. +7 more
core +1 more source