Results 1 to 10 of about 12,701 (190)
Continuous proline catalysis via leaching of solid proline [PDF]
Beilstein Journal of Organic Chemistry, 2011 Herein, we demonstrate that a homogeneous catalyst can be prepared continuously via reaction with a packed-bed of a catalyst precursor. Specifically, we perform continuous proline catalyzed α-aminoxylations using a packed-bed of L-proline.
Suzanne M. Opalka +2 more
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N-acetyl proline-glycine-proline: implications for neurological disorders
Neural Regeneration Research, 2016 N-acetyl proline-glycine-proline (ac-PGP) is a matrix-derived chemoattractant, or matrikine, produced by the degradation of collagen. Ac-PGP was first identified in studies of alkali eye injury in rabbits (Pfister et al., 1995). The molecule was found to be a potent neutrophil chemoattractant and application of ac-PGP to the eye results in intense ...
Jeff W Hill, Edwin M Nemoto
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Biomolecules, 2021 L-proline (proline) is a key regulator of embryogenesis, placental development, and fetal growth. However, the underlying mechanisms that support the beneficial effects of proline are largely unknown.
Ning Liu +7 more
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Current Plant Biology, 2023 Proline/P5C cycle between mitochondria and cytosol, play important roles in energy supply and ROS (Reactive oxygen species) generation in mammalian cell.
Wenhan Ying +6 more
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The sodium/proline transporter PutP of Helicobacter pylori. [PDF]
PLoS ONE, 2013 Helicobacter pylori is cause of chronic gastritis, duodenal ulcer and gastric carcinoma in humans. L-proline is a preferred energy source of the microaerophilic bacterium. Previous analyses revealed that HpputP and HpputA, the genes that are predicted to
Araceli Rivera-Ordaz +8 more
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Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome. [PDF]
PLoS ONE, 2013 Proline is an anomalous amino acid. Its nitrogen atom is covalently locked within a ring, thus it is the only proteinogenic amino acid with a constrained phi angle.
Alexander A Morgan, Edward Rubenstein
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Proline transporters ProT and PutP are required for Staphylococcus aureus infection.
PLoS Pathogens, 2023 Proline acquired via specific transporters can serve as a proteinogenic substrate, carbon and nitrogen source, or osmolyte. Previous reports have documented that Staphylococcus aureus, a major community and nosocomial pathogen, encodes at least four ...
McKenzie K Lehman +5 more
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Proline Transport and Growth Changes in Proline Transport Mutants of Staphylococcus aureus
Microorganisms, 2022 Staphylococcus aureus is a major cause of skin/soft tissue infections and more serious infections in humans. The species usually requires the importation of proline to be able to survive. Previous work has shown that single mutations in genes that encode
William R. Schwan
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Enzymatic production of trans‐4‐hydroxy‐l‐proline by proline 4‐hydroxylase
Microbial Biotechnology, 2021 Summary Trans‐4‐hydroxy‐l‐proline (Hyp) is a useful chiral building block for production of many nutritional supplements and pharmaceuticals. However, it is still challenging for industrial production of Hyp due to heavy environmental pollution and low ...
Xiulai Chen +4 more
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Proline Isomerization: From the Chemistry and Biology to Therapeutic Opportunities
Biology, 2023 Proline isomerization, the process of interconversion between the cis- and trans-forms of proline, is an important and unique post-translational modification that can affect protein folding and conformations, and ultimately regulate protein functions and
Deepti Gurung +5 more
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