Results 11 to 20 of about 21,177 (122)
AN ENZYMATIC RESOLUTION OF PROLINE
Journal of Biological Chemistry, 1951 Douglas Hamer, JesseP. Greenstein
openalex +4 more sources
DETERMINATION OF PROLINE IN MIXTURES CONTAINING l- AND dl-PROLINE
Journal of Biological Chemistry, 1940 William H. Stein, Max Bergmann
openalex +3 more sources
Continuous proline catalysis via leaching of solid proline [PDF]
Beilstein Journal of Organic Chemistry, 2011 Herein, we demonstrate that a homogeneous catalyst can be prepared continuously via reaction with a packed-bed of a catalyst precursor. Specifically, we perform continuous proline catalyzed α-aminoxylations using a packed-bed of L-proline. The system relies on a multistep sequence in which an aldehyde and thiourea additive are passed through a column ...
D. Tyler McQuade +2 more
openaire +4 more sources
Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline [PDF]
Molecules, 2017 Proline utilization A (PutA) is a bifunctional flavoenzyme that catalyzes the two-step oxidation of l-proline to l-glutamate using spatially separated proline dehydrogenase (PRODH) and l-glutamate-γ-semialdehyde dehydrogenase (GSALDH) active sites. Substrate inhibition of the coupled PRODH-GSALDH reaction by proline is a common kinetic feature of PutAs,
Korasick, David A. +4 more
openaire +4 more sources
Proceedings of the National Academy of Sciences, 2006 Protein misfolding is now recognized to be a major contributing factor in a number of protein folding diseases, including amyotropic laterial sclerosis, cystic fibrosis, Alzheimer's disease, Parkinson's disease, and a host of many different amyloidosis diseases.
openaire +3 more sources
Microdetermination of Proline in Serum [PDF]
Clinical Chemistry, 1965 Abstract An accurate method for determination of proline in serum has been adapted to a micro scale, with good results. Acidic ethanol is used as a serum deproteinizing agent prior to development of color with ninhydrin and its extraction into benzene. The range of accuracy is ± 3.0% with as little as 0.2 ml. serum.
George K. Summer, Norris O. Roszel
openalex +4 more sources
Proline biosynthesis in a proline-accumulating barley mutant
Phytochemistry, 1984 Abstract A barley ( Hordeum vulgare L.) mutant, R5201, selected for resistance to 4 mM trans -4-hydroxyproline had a 3–6 fold increase in the soluble proline content of the leaf compared with the parent cultivar, Maris Mink. The mutant converted more [U- 4 C]glutamic acid to free proline in the leaves than Maris Mink but incorporation into protein ...
Kueh, J. S. H. +3 more
openaire +2 more sources
An Advance in Proline Ligation [PDF]
Journal of the American Chemical Society, 2011 Native chemical ligation (NCL) is widely applicable for building proteins in the laboratory. Since the discovery of this method, many strategies have been developed to enhance its capability and efficiency. Because of the poor reactivity of proline thioesters, ligation at a C-terminal proline site is not readily accomplished.
Samuel J. Danishefsky +4 more
openaire +3 more sources
Advances in Proline Ligation [PDF]
Journal of the American Chemical Society, 2012 Application of native chemical ligation logic to the case of an N-terminal proline is described. Two approaches were studied. One involved incorporation of a 3R-substituted thiyl-proline derivative. Improved results were obtained from a 3R-substituted selenol function, incorporated in the context of an oxidized dimer.
Suwei Dong +6 more
openaire +3 more sources
Journal of Agricultural and Food Chemistry, 2016 The aim of this study was to identify and quantify the release of antihypertensive tripeptides valine-proline-proline (VPP) and isoleucine-proline-proline (IPP) during in vitro oro-gastro-intestinal (OGI) digestion of bovine skimmed milk. The experimental approach combined the recently developed harmonized static in vitro digestion (IVD) model and ...
RUTELLA, GIUSEPPINA SEFORA +3 more
openaire +3 more sources