Results 21 to 30 of about 21,177 (122)
Bioscience Reports, 1997 Proline-glycine, proline-leucine and proline-valine dipeptides and their retro variants were used in the experiments to study the effects of pretreatment (imprinting) in Tetrahymena, by investigating fluorescein isothiocyanate (FITC)-conjugated peptide binding.
Péter Kovács, György Csaba
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A Proline Kink in GWALP23 [PDF]
Biophysical Journal, 2011 GWALP23 (acetyl-GGALW5LALALALALALALW19LAGA-ethanolamide) is a proven model membrane-spanning peptide (see JACS 130, 12584) that moves “beyond” WALP family peptides by employing, for the purpose of interfacial anchoring, only one tryptophan residue on either end of a central alpha-helical core sequence.
Stanley J. Opella +6 more
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Activation entropy of electron transfer reactions [PDF]
, 2005 We report microscopic calculations of free energies and entropies for intramolecular electron transfer reactions. The calculation algorithm combines the atomistic geometry and charge distribution of a molecular solute obtained from quantum calculations with the microscopic polarization response of a polar solvent expressed in terms of its polarization ...
arxiv +1 more source
Influence of Proline Deficiency on Enzymes of Proline Metabolism in the Chick
Poultry Science, 1973 Abstract Experiments were conducted to determine the effect of dietary proline on the activity of enzymes of proline metabolism. The omission of proline from the diet for young chicks was without effect on kidney arginase, proline oxidase, Δ1-pyrroline-5-carboxylic acid dehydrogenase; and kidney and liver ornithine-δ-transaminase and Δ1-pyrroline-5 ...
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Is Amino-Acid Homochirality Due To Asymmetric Photolysis In Space? [PDF]
arXiv, 1999 Amino acids occurring in proteins are, with rare exceptions, exclusively of the L-configuration. Among the many scenarios put forward to explain the origin of this chiral homogeneity (i.e., homochirality), one involves the asymmetric photolysis of amino acids present in space, triggered by circularly polarized UV radiation.
arxiv
Frontiers in Bioscience, 2012 Proline plays a special role in cancer metabolism. Proline oxidase (POX), a.k.a. proline dehydrogenase (PRODH), is among a few genes induced rapidly and robustly by P53, the tumor suppressor. Ectopic expression of POX under control of tet-off promoter initiated mitochondrial apoptosis. The mechanism activated by POX is mediated by its production of ROS.
Wei Liu, James M Phang
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Personalized Metabolic Analysis of Diseases [PDF]
arXiv, 2020 The metabolic wiring of patient cells is altered drastically in many diseases, including cancer. Understanding the nature of such changes may pave the way for new therapeutic opportunities, as well as the development of personalized treatment strategies for patients.
arxiv
A Rational Approach to Ring Flexibility in Internal Coordinate Dynamics [PDF]
arXiv, 1998 Internal coordinate molecular dynamics (ICMD) is an efficient method for studying biopolymers, but it is readily applicable only to molecules with tree topologies, that is with no internal flexible rings. Common examples violating this condition are prolines and loops closed by S-S bridges in proteins.
arxiv
Can the roles of polar and non-polar moieties be reversed in non-polar solvents? [PDF]
arXiv, 2020 Using thermodynamics integration, we study the solvation free energy of 18 amino acid side chain equivalents in solvents with different polarity, ranging from the most polar water to the most non-polar cyclohexane. The amino acid side chain equivalents are obtained from the 20 natural amino acids by replacing the backbone part with a hydrogen atom, and
arxiv
A 2D IR Study of Isotope-Edited Variants of the Elastin-like GVGVPGVG Peptide and the Size Dependent Behavior of (VPGVG)n [PDF]
arXiv, 2017 This study uses two-dimensional infrared (2D IR) spectroscopy in conjunction with isotope labeling and spectral modeling from molecular dynamics simulations to identify the dominant turn conformations that exist in equilibrium ensembles of the (VPGVG)n family of intrinsically disordered elastin-like peptides.
arxiv