Results 221 to 230 of about 47,460 (254)

Microbial Proline Racemase–Proline Dehydrogenase Cascade for Efficient Production of d-proline and N-boc-5-hydroxy-l-proline from l-proline

Applied Biochemistry and Biotechnology, 2022
D-proline and N-boc-5-hydroxy-L-proline are key chiral intermediates in the production of eletriptan and saxagliptin, respectively. An efficient proline racemase-proline dehydrogenase cascade was developed for the enantioselective production of D-proline.
Shiwen Xia, Hui Lin, Zhang Fanfan
exaly   +3 more sources

Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase

British Journal of Haematology, 2023
SummaryAmino acids in the bone marrow microenvironment (BMME) are a critical factor for multiple myeloma (MM) progression. Here, we have determined that proline is elevated in BMME of MM patients and links to poor prognosis in MM. Moreover, exogenous proline regulates MM cell proliferation and drug resistance.
Jingyu Zhang, Fangming Shi, Xing Liu, Xuan Wu, Cong Hu, Jiaojiao Guo, Qin Yang, Jiliang Xia, Yanjuan He, Gang An, Lugui Qiu, Xiangling Feng, Wen Zhou   +12 more
openaire   +2 more sources

Proline Dehydrogenase — A New Enzyme for Pollen

Biochemie Und Physiologie Der Pflanzen, 1976
Summary Using quantitative biochemical procedures, the distribution of proline dehydrogenase in pollengrains and pollen tubes of Crotalaria juncea L. is demonstrated for the first time. Increased accumulation of proline in the dormant pollen and its subsequent decrease in the germinating phase along with the increased activity of proline ...
C P Malik, M B Singh
exaly   +2 more sources

Studies on the inner mitochondrial membrane localization of proline dehydrogenase

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1977
1. The site of proline dehydrogenase (EC 1.5.99.-) activity in blowfly (Phormia regina) flight muscle mitochondria has been investigated employing the inner membrane-impermeable Fe(CN)63-as electron acceptor. Antimycin had no inhibitory effect on ferricyanide reduction due to proline dehydrogenase activity. Ferricyanide reductase activity due to inside
E, Balboni, R I, Hecht
openaire   +2 more sources

Prolidase‐proline dehydrogenase/proline oxidase‐collagen biosynthesis axis as a potential interface of apoptosis/autophagy

BioFactors, 2016
AbstractProlidase is a cytosolic imidodipeptidase that specifically splits imidodipeptides with C‐terminal proline or hydroxyproline. The enzyme plays an important role in the recycling of proline from imidodipeptides for resynthesis of collagen and other proline‐containing proteins.
Ilona, Zareba, Jerzy, Palka
openaire   +2 more sources

Allohydroxy-d-proline dehydrogenase

Archives of Microbiology, 1977
Growth of Pseudomonas aeruginosa PA01 on isomers of hydroxyproline induced the synthesis of an allohydroxy-D-proline dehydrogenase. The enzyme resembled the D-alanine dehydrogenase of this organism in its association with the particulate fraction and its linkage to oxygen through a cytochrome-containing respiratory chain, but differed from this and ...
A J, Bater, W A, Venables, S, Thomas
openaire   +2 more sources

Proline Dehydrogenase from Escherichia coli K12

European Journal of Biochemistry, 1983
We have examined the oxidative activities of inverted cytoplasmic membrane preparations from Escherichia coli bearing proline dehydrogenase. Our measurements include both direct substrate: 2,6‐dichloroindophenol and substrate: O2 oxidoreductase assays and the 9‐aminoacridine fluorescence assay for proton translocation, employing succinate and NADH ...
J L, Abrahamson, L G, Baker, J T, Stephenson, J M, Wood   +3 more
openaire   +2 more sources

Exercise Reveals Proline Dehydrogenase as a Potential Target in Heart Failure

Progress in Cardiovascular Diseases, 2019
The benefits of physical activity in cardiovascular diseases have long been appreciated. However, the molecular mechanisms that trigger and sustain the cardiac benefits of exercise are poorly understood, and it is anticipated that unveiling these mechanisms will identify novel therapeutic targets.
Moreira, Jose B.N., Wohlwend, Martin, Fenk, Simone, Åmellem, Ingrid, Flatberg, Arnar, Kraljevic, Jasenka, Marinovic, Jasna, Ljubkovic, Marko, Bjørkøy, Geir, Wisløff, Ulrik   +9 more
openaire   +3 more sources

Importance of Proline Dehydrogenase in Proline Protection against Oxidative Stress

Free Radical Biology and Medicine, 2010
Sathish Kumar Natarajan, Donald F Becker
openaire   +1 more source

Functional characterisation of proline dehydrogenase in Arabidopsis thaliana

2000
info:eu-repo/semantics ...
Mani, Srikrishnan, Van de Cotte, Brigitte, Van Montagu, Marc, Verbruggen, Nathalie   +3 more
openaire   +1 more source