Epibrassinolide and melatonin co-treatment enhances salt tolerance in tomato plants by coordinating photosynthetic efficiency, proline accumulation, and antioxidant defense. [PDF]
Yusuf M, Khan TA, Saeed T.
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Amino Acid Metabolism in Liver Mitochondria: From Homeostasis to Disease. [PDF]
Erdal R, Birsoy K, Unlu G.
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Effects of variety degeneration on yield formation, quality traits and 2-acetyl-1-pyrroline biosynthesis in high-quality Japonica rice. [PDF]
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PRODH Regulates Tamoxifen Resistance through Ferroptosis in Breast Cancer Cells. [PDF]
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Beyond neurotransmission: dopamine as an emerging biotic and abiotic stress regulator in plants. [PDF]
Shinde D, Pareek S.
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Neurological Insights into 16p11.2- And 22q11.2-Related Disorders: A Mini-Review. [PDF]
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Epibrassinolide seed priming alleviates alkaline stress by enhancing antioxidant defense in dragonhead plants. [PDF]
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Proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia susceptibility: a meta-analysis
Metabolic Brain Disease, 2017Previous studies have been conducted to explore the association between proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia (SZ) susceptibility, but providing the controversial results. Here we performed this meta-analysis to determine whether PRODH variants were associated with SZ risk.
Xingzhi Guo, Rui Li, Guo Xingzhi
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Studies on Schizophrenia, so far reveal a complex picture of neurological malfunctioning reported to be strongly associated with proline dehydrogenase (PRODH). This study employs in silico hybrid approach for virtual screening and molecular docking followed by pharmacophore identification and structural modeling.
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Type I hyperprolinemia (HPI) is an autosomal recessive disorder caused by proline oxidase deficiency. This enzyme is encoded by the proline dehydrogenase (PRODH) gene on 22q11. The functional consequences of different PRODH mutations on proline oxidase activity have been characterized in vitro.
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