Results 141 to 150 of about 204,753 (161)

Metabolomic and transcriptomic landscape of the bovine uterine lumen during the second week of the estrous cycle. [PDF]

open access: yesJ Anim Sci Biotechnol
Waheed A   +8 more
europepmc   +1 more source

Type I hyperprolinemia and proline dehydrogenase (PRODH) mutations in four Italian children with epilepsy and mental retardation

open access: yesPsychiatric Genetics, 2008
Type I hyperprolinemia (HPI) is an autosomal recessive disorder caused by proline oxidase deficiency. This enzyme is encoded by the proline dehydrogenase (PRODH) gene on 22q11. The functional consequences of different PRODH mutations on proline oxidase activity have been characterized in vitro.
DI ROSA, GABRIELLA   +10 more
openaire   +4 more sources

Proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia susceptibility: a meta-analysis

Metabolic Brain Disease, 2017
Previous studies have been conducted to explore the association between proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia (SZ) susceptibility, but providing the controversial results. Here we performed this meta-analysis to determine whether PRODH variants were associated with SZ risk.
Xingzhi Guo, Rui Li
exaly   +3 more sources

Pharmacoinformatics and molecular docking studies reveal potential novel Proline Dehydrogenase (PRODH) compounds for Schizophrenia inhibition

Medicinal Chemistry Research, 2016
Studies on Schizophrenia, so far reveal a complex picture of neurological malfunctioning reported to be strongly associated with proline dehydrogenase (PRODH). This study employs in silico hybrid approach for virtual screening and molecular docking followed by pharmacophore identification and structural modeling.
Arslan Sehgal
exaly   +2 more sources

Abstract 5402: A new anticancer strategy based on inhibiting mitochondrial proline dehydrogenase (PRODH) and exploiting synthetic lethal interactions with p53 restoration and/or glutaminase (GLS1) inhibition

Cancer Research, 2015
Abstract From prokaryotes to the highest eukaryotes, proline is catabolized by a unique and structurally conserved flavoprotein, proline dehydrogenase (PRODH). In eukaryotes PRODH associates with the inner mitochondrial membrane and catalyzes the first and rate limiting catabolic step, transferring two electrons to the electron transport
Gary K. Scott   +5 more
openaire   +1 more source

Proline dehydrogenase 1 (PRODH; POX)

Science-Business eXchange, 2012
openaire   +1 more source

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