Circ_0000705 facilitates proline metabolism of esophageal squamous cell carcinoma cells by targeting miR-621/PYCR1 axis [PDF]
Discover Oncology, 2022 CircRNAs have been found to play crucial roles in the metabolism and progression of cancers, but their roles and mechanisms in esophageal squamous cell carcinoma (ESCC) have not been fully elucidated.
Cui-juan Qian +5 more
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Hydrogen Sulfide Treatment Alleviates Chilling Injury in Cucumber Fruit by Regulating Antioxidant Capacity, Energy Metabolism and Proline Metabolism [PDF]
Foods, 2022 Although low-temperature storage could maintain the quality of fruits and vegetables, it may also result in chilling injury (CI) in cold-sensitive produce, such as cucumbers.
Jingda Wang +4 more
doaj +2 more sources
The key enzyme PYCR1 in proline metabolism: a dual driver of cancer progression and fibrotic remodeling [PDF]
Journal of Enzyme Inhibition and Medicinal ChemistryPyrroline-5-Carboxylate Reductase 1 (PYCR1), a member of the PYCR family, is a key enzyme in the proline biosynthesis pathway. Notably, PYCR1 was originally identified via genetic disease research, linking its mutations to the occurrence of cutis laxa ...
Peng Guo +13 more
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Hepatitis C Virus Dysregulates Polyamine and Proline Metabolism and Perturbs the Urea Cycle [PDF]
CellsHepatitis C virus (HCV) is an oncogenic virus that causes chronic liver disease in more than 80% of patients. During the last decade, efficient direct-acting antivirals were introduced into clinical practice.
Natalia F. Zakirova +17 more
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Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells [PDF]
Experimental and Molecular MedicineFerritin, comprising heavy (FTH1) and light (FTL) chains, is the main iron storage protein, and pancreatic cancer patients exhibit elevated serum ferritin levels.
Ji Min Park +14 more
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Targeting the glutamine-arginine-proline metabolism axis in cancer [PDF]
Journal of Enzyme Inhibition and Medicinal ChemistryMetabolic abnormalities are an important feature of tumours. The glutamine-arginine-proline axis is an important node of cancer metabolism and plays a major role in amino acid metabolism.
Di Wang +6 more
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Proline metabolism in cancer [PDF]
Amino Acids, 2021 Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the body. Recent studies have shown that proline metabolism plays an important role in metabolic reprogramming and affects the occurrence and development of cancer.
Pengyu Geng, Wangshu Qin, Guowang Xu
openaire +4 more sources
Journal of Plant Interactions, 2022 It has been discovered that many plants accumulate proline in response to osmotic stress. However, the interaction between salinity stress and proline metabolism-related genes has not been unequivocally identified in Spartina alterniflora.
Yang Zhao +4 more
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Horticultural Plant Journal, 2022 Proline accumulation has been shown to occur in plants in response to various environmental stresses. Although proline metabolism-related genes have been functionally characterized, the inter-organ transport of proline in stressed plants remains unclear.
Zhongyuan Wang +6 more
doaj +1 more source
NITROGEN METABOLISM OF SOYBEAN AT SATURATED SOIL CULTURE AND WATERING CULTIVATION OF FARMER’S SYSTEM IN CONDITIONS OF TIDAL LAND [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2023 This research aimed to study the effect of the water-saturated cultivation system of Tidal land on nitrogen metabolism in soybean. Treatment was growing plants on benches, at the different water levels of trenches-which were 15 cm, 20 cm, and 25 cm from ...
Mapegau M. +4 more
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