Results 1 to 10 of about 28,260 (185)
Prolyl Isomerase, Pin1, Controls Meiotic Progression in Mouse Oocytes [PDF]
Cells, 2022 During meiotic maturation, accurate progression of meiosis is ensured by multiple protein kinases and by signal transduction pathways they are involved in. However, the mechanisms regulating the functions of phosphorylated proteins are unclear.
Yumi Hoshino, Takafumi Uchida
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Roles of peptidyl prolyl isomerase Pin1 in viral propagation [PDF]
Frontiers in Cell and Developmental Biology, 2022 Peptidyl-prolyl isomerase (PPIase) is a unique enzyme that promotes cis-trans isomerization of a proline residue of a target protein. Peptidyl-prolyl cis-trans isomerase NIMA (never in mitosis A)-interacting 1 (Pin1) is a PPIase that binds to the pSer ...
Machi Kanna +7 more
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The prolyl isomerase Pin1 stabilizes NeuroD during differentiation of mechanoreceptors [PDF]
Frontiers in Cell and Developmental Biology, 2023 The peptidyl prolyl cis-trans isomerase Pin1 plays vital roles in diverse cellular processes and pathological conditions. NeuroD is a differentiation and survival factor for a subset of neurons and pancreatic endocrine cells.
Liqun Zhao +7 more
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Prolyl-Isomerase Pin1 Controls Key fMLP-Induced Neutrophil Functions [PDF]
Biomedicines, 2021 Neutrophils are key cells of the innate immune and inflammatory responses. They are the first blood cells to migrate to the infection site where they release high amounts of reactive oxygen species (ROS) and several peptides and enzymes required for ...
Samia Bedouhene +6 more
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Distribution of Peptidyl-Prolyl Isomerase (PPIase) in the Archaea [PDF]
Frontiers in Microbiology, 2021 Cis-trans isomerization of the peptide bond prior to proline is an intrinsically slow process but plays an essential role in protein folding. In vivo cis-trans isomerization reaction is catalyzed by Peptidyl-prolyl isomerase (PPIases), a category of ...
Anchal, Vineeta Kaushik, Manisha Goel
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Post-translational Modifications of the Peptidyl-Prolyl Isomerase Pin1 [PDF]
Frontiers in Cell and Developmental Biology, 2020 The peptidyl-prolyl cis/trans isomerase (PPIase) Pin1 is a unique enzyme that only binds to Ser/Thr-Pro peptide motifs after phosphorylation and regulates the conformational changes of the bond.
Dongmei Chen, Long Wang, Tae Ho Lee
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Prolyl Isomerase Pin1 in Human Cancer: Function, Mechanism, and Significance [PDF]
Frontiers in Cell and Developmental Biology, 2020 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is an evolutionally conserved and unique enzyme that specifically catalyzes the cis-trans isomerization of phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif and, subsequently ...
Wenchen Pu, Yuanyuan Zheng, Yong Peng
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Prolyl isomerase pin1 protects mice from endotoxin shock.
PLoS ONE, 2011 BackgroundProlyl isomerase Pin1 may be involved in innate immunity against microbial infection, but the mechanism how Pin1 controls the innate immunity is poorly understood.Methodology/principal findingsInjection of lipopolysaccharide (LPS) into the mice
Hirotada Akiyama +4 more
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Frontiers in Genetics, 2021 Objective: The aim of the present study was to construct a prognostic model based on the peptidyl prolyl cis–trans isomerase gene signature and explore the prognostic value of this model in patients with hepatocellular carcinoma.Methods: The ...
Huadi Shi +6 more
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Cells, 2022 Antibodies are central effectors of the adaptive immune response, widespread used therapeutics, but also potentially disease-causing biomolecules. Antibody folding catalysts in the plasma cell are incompletely defined. Idiopathic pulmonary fibrosis (IPF)
Stefan Preisendörfer +23 more
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