Results 121 to 130 of about 43,079 (212)
The role of peroxiredoxins in cancer [PDF]
, 2017 Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO +4 more
core +1 more source
Crosstalk between p53 modifiers at PML bodies
Molecular & Cellular Oncology, 2018 Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage.
Sonja Matt, Thomas G Hofmann
doaj +1 more source
Marine Drugs, 2005 : Verrucarin A is an inhibitor of protein synthesis. In this study, we examined the inhibitory action of verrucarin A on signal molecules. Verrucarin A partially inhibited the IL-8 production of a PMA-stimulated promyelocytic leukemia cell line (HL-60 ...
Tadashi Kasahara +5 more
doaj +1 more source
Promyelocytic leukemia protein regulates angiogenesis and epithelial-mesenchymal transition to limit metastasis in MDA-MB-231 breast cancer cells. [PDF]
Mol Oncol, 2023 Vogiatzoglou AP +7 more
europepmc +1 more source
Regulation of epithelial sodium transport by promyelocytic leukemia zinc finger protein
American Journal of Physiology-Renal Physiology, 2008 Aldosterone is the principal regulator of Na homeostasis, and thereby blood pressure. One of the main targets of aldosterone is the epithelial Na channel (ENaC) located in the apical membrane of target cells. Previous studies identified several genes involved in the regulation of ENaC such as SGK1; however, SGK1 knockout mice have only a mild salt ...
Anikó, Náray-Fejes-Tóth +2 more
openaire +3 more sources
Frontiers in Oncology, 2013 The role of the promyelocytic leukemia protein (PML) has been widely tested in many different contexts, as attested by the hundreds of papers present in the literature.
Massimiliano eMazza +1 more
doaj +1 more source
LDL Affects the Immunomodulatory Response of Endothelial Cells by Modulation of the Promyelocytic Leukemia Protein (PML) Expression via PKC. [PDF]
Int J Mol Sci, 2023 Roos K, Berkholz J.
europepmc +1 more source
Tumor Biology, 2015 It has been shown that Yes-associated protein (YAP) acts as a transcriptional co-activator to regulate p73-dependent apoptosis in response to DNA damage in some cell types, and promyelocytic leukemia (PML) protein is involved in the regulation loop through stabilization of YAP through sumoylation.
Zhipeng, Xu +4 more
openaire +2 more sources
Post-translational modifications of PML: consequence and implications
Frontiers in Oncology, 2013 The tumor suppressor promyelocytic leukemia protein (PML) predominantly resides in a structurally distinct sub-nuclear domain called PML nuclear bodies (NBs).
Xiwen eCheng, Hung-Ying eKao
doaj +1 more source
3C protease of enterovirus 71 cleaves promyelocytic leukemia protein and impairs PML-NBs production. [PDF]
Virol J, 2021 Li Z, Wu Y, Li H, Li W, Tan J, Qiao W.
europepmc +1 more source