Results 101 to 110 of about 3,564,161 (186)

A bayesian network model of proteins' association with promyelocytic leukemia (PML) nuclear bodies

, 2010
The modularity that nuclear organization brings has the potential to explain the function of aggregates of proteins and RNA. Promyelocytic leukemia nuclear bodies are implicated in important regulatory processes.
Boden, Mikael, Bailey, Timothy L., Bailey, Timothy, Burrage, Kevin, Dellaire, Graham   +4 more
core   +1 more source

The promyelocytic leukemia zinc finger protein (PLZF): two decades of molecular oncology

Frontiers in Oncology, 2012
The promyelocytic leukemia zinc finger protein (PLZF), also known as Zbtb16 or Zfp145, was first identified in a patient with acute promyelocytic leukemia, where a reciprocal chromosomal translocation t(11;17)(q23;q21) resulted in a fusion with the RARA ...
Bandar Ali Suliman, Bandar Ali Suliman, Dakang eXu, Bryan Raymond George Williams   +3 more
doaj   +1 more source

Continuing high early death rate in acute promyelocytic leukemia: a population-based report from the Swedish Adult Acute Leukemia Registry

, 2011
Our knowledge about acute promyelocytic leukemia (APL) patients is mainly based on data from clinical trials, whereas population-based information is scarce.
S Lehmann, Derolf, A. R., M Höglund, S Deneberg, Antunovic, P, Juliusson, G, Stockelberg, D.,, Möllgård, L, Wennstrom, L., Wennström, L, A Ravn, P Antunovic, Ravn, A., Carlsson, L., Derolf, A Rangert, Wennstrom, L.,, Antunovic, P., Hoglund, M.,, Rangert Derolf, Å, Lehmann, S.,, Tidefelt, U, D Stockelberg, Carlsson, L, Hoglund, M., Antunovic, Petar,, A Wahlin, Carlsson, L.,, Lehmann, S, L Möllgård, G Juliusson, Å Rangert Derolf, Deneberg, S., Tidefelt, Ulf,, Höglund, Martin,, Stockelberg, D, Wahlin, A, Lund University., Juliusson, Gunnar, L Wennström, Mollgard, L., Derolf, A. Rangert, Juliusson, Gunnar,, Ravn, S, Ravn, A, Lehmann, S., Juliusson, G., Wennström, Lovisa,, Stockelberg, D., Wahlin, A., Tidefelt, U., Rangert Derolf, A.,, Lehmann, Sören, Mollgard, L.,, Deneberg, S, Höglund, M, Ravn, A.,, U Tidefelt, Wahlin, A.,, Wahlin, Anders,, Juliusson, G.,, Tidefelt, U.,, L Carlsson, Stockelberg, Dick,, Högberg, M, Deneberg, S.,   +64 more
core   +1 more source

Verrucarin A Inhibition of MAP Kinase Activation in a PMA-stimulated Promyelocytic Leukemia Cell Line

Marine Drugs, 2005
: Verrucarin A is an inhibitor of protein synthesis. In this study, we examined the inhibitory action of verrucarin A on signal molecules. Verrucarin A partially inhibited the IL-8 production of a PMA-stimulated promyelocytic leukemia cell line (HL-60 ...
Tadashi Kasahara, Yoshio Honma, Hisayoshi Kobayashi, Kyoko Akano, Michio Namikoshi, Taiko Oda   +5 more
doaj   +1 more source

Promyelocytic leukemia protein regulates angiogenesis and epithelial-mesenchymal transition to limit metastasis in MDA-MB-231 breast cancer cells. [PDF]

Mol Oncol, 2023
Vogiatzoglou AP, Spanou S, Sachini N, Drakos E, Nikolaou C, Makatounakis T, Kretsovali A, Papamatheakis J.   +7 more
europepmc   +1 more source

All‐Trans Retinoic Acid Promotes Endometrial Regeneration and Angiogenesis Associated With Wnt/β‐Catenin Signaling in a Mouse Model of Intrauterine Adhesion

iNew Medicine, Volume 2, Issue 3, September 2026.
ATRA promotes endometrial regeneration, angiogenesis, and uterine receptivity in intrauterine adhesion, at least in part through activation of Wnt/β‐catenin signaling. ABSTRACT Objective To investigate the therapeutic effects of all‐trans retinoic acid (ATRA) on endometrial repair and the underlying mechanisms.
Ting Luo, Ting Liao, Yunxia Cao, Zhaolian Wei   +3 more
wiley   +1 more source

METTL7A‐Dependent m6A Methylation Orchestrates CXCR4hi Neutrophil Pathogenicity and NETosis in Skin Inflammation

MedComm, Volume 7, Issue 9, September 2026.
In psoriasis, METTL7A is upregulated in aged CXCR4hi neutrophils, where it stabilizes PLSCR1 mRNA via m6A modification to enhance reactive oxygen species (ROS) production and neutrophil extracellular trap (NET) formation, thereby exacerbating disease severity.
Wanting Liu, Jinkai Liang, Huiyi Quan, Xuan Liu, Kang Li, Xin Tang, Jiaqi Wang, Yunfeng Gu, Yaxing Bai, Ke Xue, Zhiguo Li, Xiaolei Su, Erle Dang, Jiaoling Chen, Gang Wang, Shuai Shao   +15 more
wiley   +1 more source

Is PML a tumor suppressor?

Frontiers in Oncology, 2013
The role of the promyelocytic leukemia protein (PML) has been widely tested in many different contexts, as attested by the hundreds of papers present in the literature.
Massimiliano eMazza, Pier Giuseppe ePelicci   +1 more
doaj   +1 more source

Promyelocytic Leukemia Protein Potently Restricts Human Cytomegalovirus Infection in Endothelial Cells. [PDF]

Int J Mol Sci, 2022
Seitz S, Heusel AT, Stamminger T, Scherer M.   +3 more
europepmc   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao, Jinxiu Qian, Qiqiong Liu, Wanting Ye, Ying Xing, Xiuyun Bai, Rongjun Deng, Jue Yang, Cheng Lu, Cheng Xiao, Yuanyan Liu   +10 more
wiley   +1 more source