Results 111 to 120 of about 3,564,161 (186)

Estudo da associação de genes e proteínas de resistência a múltiplos fármacos (abcb1/ABCB1, abcc1/ABCC1 e lrp/LRP) com marcadores moleculares em pacientes portadores de leucemias agudas [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.Menos de 45% dos portadores de leucemias agudas (LAs) sobrevivem cinco anos após o diagnóstico. O insucesso
Moraes, Ana Carolina Rabello de
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Metaphase and Interphase Cytogenetics with Alu-PCR-amplified Yeast Artificial Chromosome Clones Containing the BCR Gene and the Protooncogenes c-raf-1, c-fms, and c-erbB-21 [PDF]

, 1992
A human yeast artificial chromosome (YAC) library was screened by polymerase chain reaction with oligonucleotide primers defined for DNA sequences of the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erB-2.
Olson, Maynard V., Riethman, Harold C., Speicher, Michael R., Cremer, Thomas, Green, Eric D., Becher, Reinhard, Konecki, David, Taniwaki, Masafumi, Lengauer, Christoph   +8 more
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Isocitrate Dehydrogenase (IDH) Mutations in Hematological Malignancies: Epidemiology, Mechanisms, and Therapeutic Strategies

MedComm – Future Medicine, Volume 5, Issue 3, September 2026.
IDH mutation is an important event in hematological malignancies. This review systematically integrates the basic mechanism of IDH mutations and combines it with the clinical translation of related research progress. It also discusses the application strategies of IDH inhibitors and feasible research directions, with the aim of providing a theoretical ...
Jinkun Xu, Haiying Bai, Lijuan Hu
wiley   +1 more source

Human surfactant protein D alters oxidative stress and HMGA1 expression to induce p53 apoptotic pathway in eosinophil leukemic cell line [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. Copyright: © 2013 Mahajan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use ...
Pandit Hrishikesh, Uday Kishore (504246), Ravi Sirdeshmukh, P. Usha Sarma (504245), Curam S Sundaram, Lakshna Mahajan (504239), Madan, T, Ajit K Yadav, Madan Taruna, Poonam Gautam, Ajit K. Yadav (504242), Curam S. Sundaram (504244), Yadav Ajit K., Ravi Sirdeshmukh (131378), Himangi Warke, P. Usha Sarma, Surolia Avadhesha, Warke Himangi, Lakshna Mahajan, Hrishikesh Pandit, Pandit, H, Sundaram, CS, Himangi Warke (504243), Sarma, PU, Poonam Gautam (131332), Sundaram Curam S., Sirdeshmukh Ravi, Sarma P. Usha, Surolia, A, Curam S. Sundaram, Avadhesha Surolia (78297), Mahajan, L, Kishore Uday, Yadav, AK, Sirdeshmukh, R, Warke, H, Taruna Madan, Kishore, U, Taruna Madan (504241), P Usha Sarma, Gautam, P, Mahajan Lakshna, Gautam Poonam, Hrishikesh Pandit (504240), Ajit K. Yadav, Avadhesha Surolia, Uday Kishore   +46 more
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Promyelocytic leukemia protein targets MK2 to promote cytotoxicity. [PDF]

EMBO Rep, 2021
Chen IT, Chen HC, Lo YH, Lai PY, Hsieh FY, Wu YH, Shih HM, Lai MZ.   +7 more
europepmc   +1 more source

Twisting the End Game: How Telomere Chromatin Modifications Shape Telomere Maintenance

Aging Cell, Volume 25, Issue 9, September 2026.
Chromatin modifications on telomeres are linked to the mode of telomere DNA replication. A coupled feedforward loop model is proposed based on these to lock the ALT cancer cells in this alternative mode of telomere replication. ABSTRACT Cell division inevitably shortens telomeric DNA owing to the end‐replication problem.
Jie Wang, Yuehui Su, Chao Chen, Yueying Li, Jiajia Han, Liping Du, Liyun Zheng, Ya‐Long Dang, Ying Peng   +8 more
wiley   +1 more source

3C protease of enterovirus 71 cleaves promyelocytic leukemia protein and impairs PML-NBs production. [PDF]

Virol J, 2021
Li Z, Wu Y, Li H, Li W, Tan J, Qiao W.
europepmc   +1 more source

Manipulation of Promyelocytic Leukemia Protein Nuclear Bodies by Marek's Disease Virus Encoded US3 Protein Kinase. [PDF]

Microorganisms, 2021
Liao Y, Lupiani B, Reddy SM.
europepmc   +1 more source

Retinoic Acid and Arsenic Trioxide sensitize Acute Promyelocytic Leukemia cells to ER stress

, 2017
Promyelocytic leukemia (APL) is characterized by the chromosomal translocation t(15:17) that results in the expression of the chimeric protein PML-RARα. The fusion of PML, a tumor suppressor that is the major component of the PML-nuclear bodies, with the
FAZI, Francesco, Divona, Mariadomenica, MASCIARELLI, SILVIA, Ottone, Tiziana, Lo Coco Francesco,, Noguera, Nelida, CAPUANO, ERNESTINA, DE PANFILIS, SIMONE   +7 more
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Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome

, 2008
Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via ...
Xuefei Cao (1700068), Yuan Chen (9740), H. Helen Lin (5469503), Xu Li (23864), Hsiu-Ming Shih (222985), David K. Ann (665043), Carlos Clavijo (13919755)   +6 more
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