Results 131 to 140 of about 3,564,161 (186)

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors [PDF]

, 2002
FLT3 mutations, either internal tandem duplications (ITDs) or aspartate residue 835 (D835) point mutations, are present in approximately one third of patients with acute myeloid leukemia (AML) and have been associated with an increased relapse rate.
Kottaridis, P.D., Gale, R.E., Bowen, D.T., Langabeer, S.E., Frew, M.E., Linch, D.C.   +5 more
core  

The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres. [PDF]

PLoS Pathog, 2020
Collin V, Gravel A, Kaufer BB, Flamand L.   +3 more
europepmc   +1 more source

Relationship between promyelocytic leukemia protein nuclear bodies and TAR DNA-binding protein-43 aggregation in spinal anterior horn cells in sporadic amyotrophic lateral sclerosis. [PDF]

J Neuropathol Exp Neurol
Mori F, Kon T, Itazawa R, Akatsu A, Miki Y, Arai A, Kurotaki H, Tomiyama M, Wakabayashi K.   +8 more
europepmc   +1 more source

Time-resolved mapping in calves reveals bovine herpesvirus 1 shift from mucosal replication to trigeminal ganglion neuroinvasion with promyelocytic leukemia protein-centered host-virus antagonism. [PDF]

Microbiol Spectr
Wang Y, Jin H, Wang F, Cheng J, Cao M, Zhou L, Liu W, Li Y.   +7 more
europepmc   +1 more source

Promyelocytic leukemia protein in mesenchymal stem cells is essential for leukemia progression. [PDF]

Ann Hematol, 2018
de Alvarenga EC, Silva WN, Vasconcellos R, Paredes-Gamero EJ, Mintz A, Birbrair A.   +5 more
europepmc   +1 more source

Promyelocytic Leukemia Protein (PML) Requirement for Interferon-induced Global Cellular SUMOylation. [PDF]

Mol Cell Proteomics, 2018
Maroui MA, Maarifi G, McManus FP, Lamoliatte F, Thibault P, Chelbi-Alix MK.   +5 more
europepmc   +1 more source

Promyelocytic Leukemia Protein (PML) Regulates Stem Cell Pluripotency Through Novel Sumoylation Targets. [PDF]

Int J Mol Sci
Spanou S, Makatounakis T, Filippopoulou C, Dougalis G, Stamatakis G, Nikolaou C, Samiotaki M, Chachami G, Papamatheakis J, Kretsovali A.   +9 more
europepmc   +1 more source

Promyelocytic leukemia protein (PML) controls breast cancer cell proliferation by modulating Forkhead transcription factors. [PDF]

Mol Oncol, 2019
Sachini N, Arampatzi P, Klonizakis A, Nikolaou C, Makatounakis T, Lam EW, Kretsovali A, Papamatheakis J.   +7 more
europepmc   +1 more source

Promyelocytic leukemia protein deficiency leads to spontaneous formation of liver tumors in hepatitis C virus transgenic mice. [PDF]

Cancer Med, 2019
Straub K, Husen P, Baba HA, Trippler M, Wedemeyer H, Herzer K.   +5 more
europepmc   +1 more source

Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A. [PDF]

Nucleic Acids Res
Gu X, Zhuang A, Yu J, Yang L, Ge S, Ruan J, Jia R, Fan X, Chai P.   +8 more
europepmc   +1 more source