Results 161 to 170 of about 136,204 (260)

3C protease of enterovirus 71 cleaves promyelocytic leukemia protein and impairs PML-NBs production. [PDF]

Virol J, 2021
Li Z, Wu Y, Li H, Li W, Tan J, Qiao W.
europepmc   +1 more source

Promyelocytic leukemia protein is required for gain of function by mutant p53.

Cancer Research, 2009
Mutations in the p53 tumor suppressor are the most common genetic events in human cancer. These mutations not only result in a loss of wild-type p53 activity, but can also lead to a gain of new oncogenic properties.
S. Haupt, Silvia Di Agostino, I. Mizrahi, Osnat Alsheich-Bartok, M. Voorhoeve, A. Damalas, G. Blandino, Y. Haupt   +7 more
semanticscholar   +1 more source

Manipulation of Promyelocytic Leukemia Protein Nuclear Bodies by Marek's Disease Virus Encoded US3 Protein Kinase. [PDF]

Microorganisms, 2021
Liao Y, Lupiani B, Reddy SM.
europepmc   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science
Acute promyelocytic leukemia (APL) accounts for 5–15% of acute myeloid leukemia cases. It is typically characterized by the (15;17) chromosomal translocation, producing the pathogenic retinoic acid receptor (RAR) alpha/promyelocytic leukemia (PML) fusion
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
doaj   +1 more source

Forkhead O Transcription Factor 4 Restricts HBV Covalently Closed Circular DNA Transcription and HBV Replication through Genetic Downregulation of Hepatocyte Nuclear Factor 4 Alpha and Epigenetic Suppression of Covalently Closed Circular DNA via Interacting with Promyelocytic Leukemia Protein. [PDF]

J Virol, 2022
Li Y, He M, Gong R, Wang Z, Lu L, Peng S, Duan Z, Feng Y, Liu Y, Gao B.   +9 more
europepmc   +1 more source

Promyelocytic leukemia (PML) gene expression is a prognostic factor in ampullary cancer patients [PDF]

, 2009
BACKGROUND: Promyelocytic leukemia (PML) tumor suppressor gene plays a key role in acute PML pathogenesis but its involvement in pathogenesis and prognosis of solid cancers has not been defined yet.
Adamo, V, Alloni, R, Antinori, A, Castri, F, Coppola, R, Crucitti, PF, Magistrelli, P, Morini, S, Perrone, G, Rabitti, C, RIZZO, Sergio, RUSSO, Antonio, Santini, D, Tonini, G., Vecchio, FM, Vincenzi, B   +15 more
core  

Disease-specific epigenetic deregulation of enhancers, transposons, and polycomb targets in acute promyelocytic leukemia

Genome Medicine
Background Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML), characterized by a fusion between the PML and RARA genes and by a block in the myeloid maturation at the promyelocytic stage.
Xiangfu Zhong, Lina Cordeddu, Angelica Gamboa-Cedeno, Sofia Bengtzén, Karl Ekwall, Andreas Lennartsson, Sören Lehmann   +6 more
doaj   +1 more source

Molecular mechanisms in haematological malignancies [PDF]

, 2009
Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto, Grech, Godfrey, Schembri-Wismayer, Pierre   +2 more
core  

C-terminal motifs in promyelocytic leukemia protein isoforms critically regulate PML nuclear body formation

Journal of Cell Science, 2017
Chuang Li, Q. Peng, X. Wan, Haili Sun, Jun Tang   +4 more
semanticscholar   +1 more source

Retraction for Bischof et al., "Human Papillomavirus Oncoprotein E7 Targets the Promyelocytic Leukemia Protein and Circumvents Cellular Senescence via the Rb and p53 Tumor Suppressor Pathways". [PDF]

Mol Cell Biol, 2020
Bischof O, Nacerddine K, Dejean A.
europepmc   +1 more source