Results 211 to 220 of about 136,204 (260)

JC Virus Agnogene Regulates Histone-Modifying Enzymes via PML-NBs: Transcriptomics in VLP-Expressing Cells. [PDF]

Viruses
Shishido-Hara Y, Yaoi T.
europepmc   +1 more source

Covalent targeting of PSMD14 by Eupalinolide B induces oncoprotein degradation and apoptosis in acute promyelocytic leukemia cells. [PDF]

RSC Chem Biol
Chu Z, Xu L, Chen H, Fan T, Hu X, Wong YK, Shi Q, Zhang J, Xu C, Wang J, Tang H.   +10 more
europepmc   +1 more source

Acute Promyelocytic Leukemia with double minute chromosomes: a rare case with high relapse risk. [PDF]

Oxf Med Case Reports
Sasaki Y, Shimada S, Kawamata N, Hayashi H, Nagao K, Kuroiwa K, Narita H, Okamura R, Watanuki M, Arai N, Yanagisawa K, Hattori N.   +11 more
europepmc   +1 more source

Role of p62 nuclear condensates in regulating ubiquitin-mediated proteasomal degradation. [PDF]

Essays Biochem
Lulu-Shimron C, Ciechanover A, Cohen-Kaplan V.   +2 more
europepmc   +1 more source

Prolonged Acute Kidney Injury and Symmetrical Peripheral Gangrene: A Rare Case Report of Acute Promyelocytic Leukemia. [PDF]

J Inflamm Res
Kong YK, Shu H, Zhang WJ, Wu CY.
europepmc   +1 more source

Identification of a novel PML exon 6 splice variant in atypical PML::RARα transcripts in acute promyelocytic leukemia. [PDF]

Ann Hematol
Chen H, Chen M, Yang Z, Liao S, Lin Y, Yan L.   +5 more
europepmc   +1 more source

Reversing the Warburg Effect: YW3-56 Induces Leukemia Differentiation via AKT-Mediated Glucose Metabolic Reprogramming. [PDF]

Pharmaceuticals (Basel)
Zhu D, Gao D, Lu Y, Chen N, Zhang L, Zhang L, Wang Y.   +6 more
europepmc   +1 more source

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Promyelocytic leukemia protein: an atherosclerosis suppressor protein?

Clinical Science, 2021
As many as 70% of cells in atherosclerotic plaque are vascular smooth muscle cell (VSMC) in origin, and pathways and proteins which regulate VSMC migration, proliferation, and phenotype modulation represent novel targets for rational drug design to ...
Cali B. Corbett, Amanda St. Paul, M. Autieri   +2 more
semanticscholar   +3 more sources

Activation of a promyelocytic leukemia–tumor protein 53 axis underlies acute promyelocytic leukemia cure

Nature Medicine, 2014
Acute promyelocytic leukemia (APL) is driven by the promyelocytic leukemia (PML)-retinoic acid receptor-α (PML-RARA) fusion protein, which interferes with nuclear receptor signaling and PML nuclear body (NB) assembly. APL is the only malignancy definitively cured by targeted therapies: retinoic acid (RA) and/or arsenic trioxide, which both trigger PML ...
Julien Ablain, K. Rice, H. Soilihi, A. Reyniès, S. Minucci, H. Thé   +5 more
semanticscholar   +3 more sources