Results 61 to 70 of about 94,443 (308)

Assessing instructional effects of proficiency-level EFL pronunciation teaching under a connected speech-based approach

Studies in Second Language Learning and Teaching, 2014
This article discusses the assessment of pronunciation instruction under a new approach to pronunciation teaching centered on the role of connected speech in the prosodic system of English.
Sasha S. Euler
doaj   +1 more source

Exploring the Relationship between Pronunciation Training and Listening Ability [PDF]

, 2019
This study was an attempt to examine the effect of pronunciation training on students’ listening ability. TOEIC listening scores of students who took a pronunciation training class for one-semester or two-semesters were compared with students who did not
Desrosiers, Lori Ann
core  

Learner Perspective on English Pronunciation Teaching in an EFL Context [PDF]

, 2013
On the basis of the findings, the learners do not seem to have aspirations to native-like pronunciation, but rather aim at achieving intelligible and fluent speech. Only few reported an accent preference (British or American).
Breitkreutz, Breitkreutz, Burgess, Burgess, Celce, Celce, Cenoz, Cenoz, Cunningham, Cunningham, Cunningsworth, Cunningsworth, Dalton, Dalton, Denzin, Denzin, Derwing, Derwing, Elina Tergujeff, Fontana, Fontana, Foote, Foote, Fraser, Fraser, Gilbert, Gilbert, Henderson, Henderson, Iivonen, Iivonen, Iivonen, Iivonen, Janicka, Janicka, Jenkins, Jenkins, Jones, Jones, Kachru, Kachru, Kumpulainen, Kumpulainen, Kvale, Kvale, Kääntä, Kääntä, Leppänen, Leppänen, Lintunen, Lintunen, Luukka, Luukka, Macdonald, Macdonald, Morley, Morley, Pihko, Pihko, Purcell, Purcell, Saito, Saito, Suomi, Suomi, Suter, Suter, Tergujeff, Tergujeff, Tergujeff, Tergujeff, Tergujeff, Tergujeff, Waniek, Waniek, Waniek, Waniek, Waniek, Waniek, Wells, Wells   +80 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Teaching Authentic English Pronounciation [PDF]

, 2011
Most of the evidence from different research and literature indicates that learners beyond the age of puberty cannot acquire authentic pronunciation of a second language, because the articulation muscles have already lost their flexibility to be able to ...
Rashtchi, Mehrdad
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Teaching and Learning Pronunciation: EFL Learners’ Views and Instructors’ Practices

e-Kafkas Eğitim Araştırmaları Dergisi
The discussion surrounding the significance of pronunciation in communication, both in a first language (L1) and a second language (L2), has been a subject of ongoing debate.
Mehmet Gazan, Nurdan Gürbüz
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Mispronounced lexical items in polish English of advanced learners [PDF]

, 2012
The present study is a report on an experiment in which 20 English Department students, all advanced learners of English, were recorded having been asked to read a list of diagnostic sentences containing 80 words known to be problematic for Poles in ...
Szpyra-Kozłowska, Jolanta
core   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source