Cocaine-and Amphetamine Regulated Transcript (CART) Peptide Is Expressed in Precursor Cells and Somatotropes of the Mouse Pituitary Gland. [PDF]
Cocaine-and Amphetamine Regulated Transcript (CART) peptide is expressed in the brain, endocrine and neuroendocrine systems and secreted into the serum. It is thought to play a role in regulation of hypothalamic pituitary functions.
Amanda H Mortensen, Sally A Camper
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Objective:Mutations of the genes encoding transcription factors which play important roles in pituitary morphogenesis, differentiation and maturation may lead to combined pituitary hormone deficiency (CPHD).
Fatma Derya Bulut +5 more
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From Pituitary Stem Cell Differentiation to Regenerative Medicine
The anterior pituitary gland is comprised of specialized cell-types that produce and secrete polypeptide hormones in response to hypothalamic input and feedback from target organs.
Maria Andrea Camilletti +3 more
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The Prop1-like homeobox gene unc-42 specifies the identity of synaptically connected neurons
Many neuronal identity regulators are expressed in distinct populations of cells in the nervous system, but their function is often analyzed only in specific isolated cellular contexts, thereby potentially leaving overarching themes in gene function ...
Emily G Berghoff +16 more
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Gradual loss of ACTH due to a novel mutation in LHX4: comprehensive mutation screening in Japanese patients with congenital hypopituitarism. [PDF]
Mutations in transcription factors genes, which are well regulated spatially and temporally in the pituitary gland, result in congenital hypopituitarism (CH) in humans.
Masaki Takagi +9 more
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Studies have demonstrated that flavonoid compounds of green propolis have antitumoral activity. STUDY DESIGN: Experimental study. AIMS: To evaluate the effect of a hydroalcoholic extract of green propolis (EPV) on chemically induced epithelial dysplasias
Danielle Rodrigues Ribeiro Cavalcante +6 more
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This study was planned to determine the effects of ethanol extract of propolis on the fermentation quality, fatty acid profile, aerobic stability, and in vitro digestibility of alfalfa silages.
Sibel Soycan Önenç +2 more
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All hormone-producing cell types of the pituitary intermediate and anterior lobes derive from prop1-expressing progenitors [PDF]
Mutations in PROP1, the most common known cause of combined pituitary hormone deficiency in humans, can result in the progressive loss of all hormones of the pituitary anterior lobe.
Keisler, Jessica L. +4 more
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Polymorphism analysis of milk yield candidate genes in turkish native goats: honamlı and hair breeds [PDF]
This study examined polymorphisms of nine genes (ADFP, AGPAT6, FOLR1, LHX3, PITX1, PITX2, PRLR, PROP1, and STAT5A) in Honamlı and Hair goats and compared allele and genotype frequencies with those reported in other breeds.
Özgecan KORKMAZ AĞAOĞLU +2 more
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Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction. [PDF]
Ames dwarf (Prop1 (df/df) ) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR) has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames ...
Oge Arum +3 more
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