Results 31 to 40 of about 2,015 (159)
Cells, 2022 Combined pituitary hormone deficiency (CPHD) is characterized by deficiency of growth hormone and at least one other pituitary hormone. Pathogenic variants in more than 30 genes expressed during the development of the head, hypothalamus, and/or pituitary
Amalia Sertedaki +7 more
doaj +1 more source
PROP1 gene mutations in a 36-year-old female presenting with psychosis
Endocrinology, Diabetes & Metabolism Case Reports, 2017 Combined pituitary hormonal deficiency (CPHD) is a rare disease that results from mutations in genes coding for transcription factors that regulate the differentiation of pituitary cells.
Durgesh Prasad Chaudhary +3 more
doaj +1 more source
Prop1-defiency results in low blood glucose levels.
, 2013 Blood glucose levels were measured in normal and Prop1 mutant mice at four ages. (A) Basal glucose levels in 3.5 to 5 week Prop1-/- mice (n = 6) were lower than Prop1+/+ (n = 10) and Prop1+/− (n = 10) mice from mixed genetic backgrounds, but the ...
Sally A. Camper (41538) +7 more
core +1 more source
No evidence for evolving hypocortisolism in Prop1 deficient animals.
, 2013 Blood plasma was collected from 3.5 to 5 wk N4B6 (Panel A) and 34 to 52 wk mixed genetic background (Panel B) animals from and the circulating ACTH levels were determined by RIA.
Sally A. Camper (41538) +7 more
core +1 more source
, 2013 RIA analysis of circulating corticosterone was carried out on serum from 8 to 10 week males (A) and females (B) of segregating the Prop1 null allele at N4 B6 prior to (white bars) and following restraint stress (black bars).
Sally A. Camper (41538) +7 more
core +1 more source
Análise molecular de PROP1, PIT1, HESX1, LHX3 e LHX4 mostra alta freqüência de mutações no PROP1 em pacientes com formas familiares de deficiência combinada de hormônios hipofisários [PDF]
, 2007 Combined Pituitary Hormone Deficiency (CPHD) is a prevalent disease in Neuroendocrinology services. The genetic form of CPHD may originate from mutations in pituitary transcription factor (PTF) genes and the pituitary image in these cases may give a clue
Vieira, Teresa C. [UNIFESP] +5 more
core +1 more source
Stem cell-associated transcription factors in non-functioning pituitary neuroendocrine tumours
Free NeuropathologyBackground: Cells with stem cell features have been described in pituitary neuroendocrine tumours (PitNETs). Transcription factors SOX2 and SOX9 are stem cell-associated markers while the pituitary progenitor marker PROP1 is involved in anterior ...
Kristin Astrid Øystese +7 more
doaj +1 more source
LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation
Aging Cell, Volume 25, Issue 9, September 2026.We present LivAge, an online aging clock that estimates murine transcriptomic age from hepatic RNA‐seq data. Externally validated, it detects accelerated aging in progeroid models and quantifies the effect of geroprotective interventions, providing an accurate, accessible, and ready‐to‐use tool for aging research.
Víctor Celemín‐Capaldi +6 more
wiley +1 more source
Frontiers in Endocrinology, 2022 Hypothalamus-pituitary-adrenal (HPA) axis plays critical roles in stress responses under challenging conditions such as hypoxia, via regulating gene expression and integrating activities of hypothalamus-pituitary-targets cells.
Tong Ying Wang +23 more
doaj +1 more source
Journal of Fish Diseases, Volume 49, Issue 7, July 2026.ABSTRACT The myxozoan endoparasite Tetracapsuloides bryosalmonae (Tb), the causative agent of proliferative kidney disease (PKD) in salmonids, has predominantly been reported in temperate regions of continental Europe and North America. Here, we present the first record of Tb in the Faroe Islands, extending the known northern distribution of the ...
Magnus Lauringson +3 more
wiley +1 more source