Results 101 to 110 of about 10,092 (236)
Activation of human NK cells by Plasmodium-infected red blood cells.
, 2012 This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Horowitz, Amir, Riley, Eleanor M
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European Journal of Immunology, Volume 54, Issue 9, September 2024.Factor D (FD) and MASP3 are two proteases that are critical for alternative pathway complement activation and represent attractive therapeutic targets for complement‐mediated human diseases. Abstract The alternative pathway (AP) plays a major role in many complement‐mediated human diseases.
Eshagh Mohammadyari +3 more
wiley +1 more source
Study of the variables associated with local complement activation in IgA nephropathy
Nefrología (English Edition), 2017 Objectives: 1. To identify the variables that are associated with urinary levels of properdin, MBL, C4d, and C5b-9 in patients with idiopathic IgA nephropathy. 2. To analyse whether urinary levels of MBL and/or C4d are useful for identifying the presence
Alfons Segarra-Medrano +6 more
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QUANTITATIVE STUDIES ON THE PROPERDIN-COMPLEMENT SYSTEM [PDF]
The Journal of Experimental Medicine, 1956 Quantitative methods have been developed for the estimation of C'3 and properdin. With these methods, the kinetics of the over-all reaction between properdin, zymosan, and C'3 were investigated. The reaction followed first order kinetics, provided zymosan was in excess, and the serum not diluted beyond 1/4.
openaire +6 more sources
Anti-factor B autoantibody in dense deposit disease [PDF]
, 2010 Dense deposit disease (DDD), also known as membranoproliferative glomerulonephritis type II, is a rare kidney disorder that is associated with dysregulation of the alternative pathway of complement.
Józsi, Mihály +4 more
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Crepuscular rays — The bright side of complement after tissue injury
European Journal of Immunology, Volume 54, Issue 9, September 2024.Traumatic injuries elicit an activation of the complement system. Due to its overwhelming nature, it's often described as harmful, while its protective effects are overlooked. This review focuses on and summarizes the advantageous aspects of complement shining as “sunbeams” through the otherwise negative‐afflicted “clouds” (i.e.
Marco Mannes +4 more
wiley +1 more source
Exosome nanovesicles: biomarkers and new strategies for treatment of human diseases
MedComm, Volume 5, Issue 8, August 2024.• Updated review of recent exosomes in liquid biopsy and disease treatment applications • Recent advances in the use of exosomes as biomarkers in disease applications • Therapies and efficacy of engineered exosome applications • Impact of exosomes on precision medicine and personalized treatment Abstract Exosomes are nanoscale vesicles of cellular ...
Chuan Xu +9 more
wiley +1 more source
Properdin Levels in Splenectomized Persons
Experimental Biology and Medicine, 1959 SummaryProperdin titers were definitely lower in 105 splenectomized persons than in 113 normal; healthy subjects. Within the splenectomized group, there was no correlation between properdin level and age of individual, age at splenectomy, and years post-splenectomy.
Harold N. Carlisle, Samuel Saslaw
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Obituary: Dale David Dykes (1945-1990) [PDF]
, 2014 On July 10, 1990, Dale D. Dykes, a well-known researcher in blood genetics, died at the University Hospital of Denver, Colorado, after suffering a massive heart attack.
Editors, Human Biology
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Prognostic value of preoperatively obtained clinical and laboratory data in predicting survival following orthotopic liver transplantation [PDF]
, 1986 Twenty‐seven clinical and laboratory data and the subsequent clinical course of 93 consecutive adult patients who underwent orthotopic liver transplantation for various chronic advanced liver diseases were analyzed retrospectively to assess the risk ...
Child +13 more
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