Results 111 to 120 of about 10,092 (236)

CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

open access: yesJournal of Neuroscience Research, Volume 102, Issue 7, July 2024.
Proteoglycans are important multifunctional components of the central and peripheral nervous systems and represent a diverse group of specialized proteins that stabilize and functionalize these tissues. Abstract Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse functional roles, this study examined how these control ...
James Melrose
wiley   +1 more source

Automatic case acquisition from texts for process-oriented case-based reasoning [PDF]

open access: yes, 2012
This paper introduces a method for the automatic acquisition of a rich case representation from free text for process-oriented case-based reasoning. Case engineering is among the most complicated and costly tasks in implementing a case-based reasoning ...
Ber, Florence Le   +3 more
core   +4 more sources

Linkage analysis in a large kindred with autosomal dominant transmission of polyglandular autoimmune disease type II (Schmidt syndrome) [PDF]

open access: yes, 1984
Schmidt syndrome (PGA syndrome type II) is a rare condition characterized by polyglandular failure. It is an autosomal dominant trait with variable expressivity that was inherited over four generations in an Indiana kindred.
Biegel, Angenieta A.   +4 more
core   +1 more source

The Emerging Clinical Usefulness of Complement Measurements [PDF]

open access: yes, 1977
Not many years ago the main purpose of “complement” seemed to be to drill holes in sheep erythrocytes. In the classic experiment which was part of every medical student’s microbiology laboratory experience, a magic stuff called complement, somewhat ...
Ruddy, Shaun
core   +1 more source

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

open access: yesFrontiers in Immunology, 2019
Properdin (FP) is a positive regulator of the immune system stimulating the activity of the proteolytically active C3 convertase C3bBb in the alternative pathway of the complement system. Here we present two crystal structures of FP and two structures of
Dennis V. Pedersen   +14 more
doaj   +1 more source

Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease? [PDF]

open access: yes, 2011
BackgroundAnorexia nervosa carries the highest mortality rate of any psychiatric disorder. Even the most critically ill anorexic patients may present with normal 'standard' laboratory values, underscoring the need for a new sensitive biomarker.
Flierl, Michael A   +5 more
core   +2 more sources

Properdin and the defence of burns against infection [PDF]

open access: bronze, 1957
E. J. L. Lowbury   +4 more
openalex   +1 more source

The complement system is activated in synovial fluid from subjects with knee injury and from patients with osteoarthritis [PDF]

open access: yes, 2016
Concentrations of C4d, C3bBbP and sTCC in synovial fluid.
André Struglics   +6 more
core   +2 more sources

Studies of the Inactivation of Phage by the Properdin System [PDF]

open access: bronze, 1958
James L. Barlow   +2 more
openalex   +1 more source

Use of electrophoresis for the determination of protein polymorphisms: application to the study of isolated human populations

open access: yesJournal of Biological Research, 2009
Third factor of complements (C3), group specific component (Gc), properdin B factor (Bf), haptoglobin (Hp) and transferrin (Tf) polymorphisms were studied in a mountain communities samples from the Italian-French Alps.
N. Salis, E. Rabino Massa
doaj   +1 more source

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