Results 1 to 10 of about 192,124 (377)

Elevated propionate and its association with neurological dysfunctions in propionic acidemia [PDF]

Frontiers in Molecular Neuroscience
Propionate, a short-chain fatty acid (SCFA), has recently attracted attention for its various health benefits. However, elevated levels of propionate in certain pathological conditions can have adverse effects. Propionic acidemia (PA) is a rare metabolic
Xiaoxin Chen, Xiaoxin Chen, Xiaoxin Chen, Qing Cheng, Guo-Fang Zhang, Guo-Fang Zhang   +5 more
doaj   +4 more sources

Quantitative Alterations in Short-Chain Fatty Acids in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis [PDF]

Biomolecules
Background: Reduced short-chain fatty acids (SCFAs) in inflammatory bowel disease (IBD) impair the gut barrier and immune function, promoting inflammation and highlighting microbiome-targeted therapies’ therapeutic potential.
Laura Chulenbayeva, Zharkyn Jarmukhanov, Karlygash Kaliyekova, Samat Kozhakhmetov, Almagul Kushugulova   +4 more
doaj   +2 more sources

Increase in colonic propionate as a method of preventing weight gain in adults aged 20–40 years: iPREVENT, a multicentre, double-blind, randomised, parallel-group trial

Efficacy and Mechanism Evaluation
Background Overweight and obesity affect over 60% of the United Kingdom population and constitute a major risk factor for the development of comorbidities.
Gary Frost, Joana C Vasconcelos, Jennifer E Pugh, Aisha Anjum, Katerina Petropoulou, George Thom, Louise McCombie, Martina Tashkova, Sumayya Alshehhi, Daphne Babalis, Leah Holroyd, Christina Prechtl, Tom Preston, Mike J Lean, Waljit Dhillo, A Toby Prevost, and Douglas Morrison   +16 more
doaj   +2 more sources

Propionate serves as a degradable control agent of citrus canker by acidifying cytoplasm and depleting intracellular ATP in Xanthomonas citri [PDF]

mBio
Citrus canker, caused by Xanthomonas citri subsp. citri (Xcc), poses a substantial threat to global citrus production. Current disease control relies on the widespread application of copper-based bactericides.
Chaoying Liu, Jingtian Zhang, Meirui Song, Xiaoli Wang, Weiwei Lv, Xiaojun Ding, Junan Zhu, Yunfei Deng, Yifei Ge, Jian Wu, Utpal Handique, Shuo Duan, Yue Shen, Feng Luo, Shi Xiao, Xiaofeng Zhou   +15 more
doaj   +2 more sources

Overexpression of GPR41 attenuated glucose production in propionate-induced bovine hepatocytes

Frontiers in Veterinary Science, 2022
Bovine liver mainly utilizes the propionate as a gluconeogenic substrate to synthesize the glucose. However, the mechanism underlying the regulatory effects of propionate on the glucose production in bovine hepatocytes remains less known.
Miao Lin, Miao Lin, Miao Lin, Maocheng Jiang, Tianyu Yang, Guoqi Zhao, Guoqi Zhao, Guoqi Zhao, Kang Zhan, Kang Zhan, Kang Zhan   +10 more
doaj   +1 more source

Protective role of colitis in inflammatory arthritis via propionate-producing Bacteroides in the gut

Frontiers in Immunology, 2023
ObjectivesTo investigate whether and how inflammatory disease in the intestine influences the development of arthritis, considering that organ-to-organ communication is associated with many physiological and pathological events.MethodsFirst, mice were ...
Hoh-Jeong Shon, Hoh-Jeong Shon, Yu-Mi Kim, Yu-Mi Kim, Kyeong Seog Kim, Kyeong Seog Kim, Jin-Ouk Choi, Jin-Ouk Choi, Sang-Hyun Cho, Sujin An, Sujin An, Se-Hyeon Park, Se-Hyeon Park, Yong-Joon Cho, Yong-Joon Cho, Yong-Joon Cho, Joo-Hong Park, Sang-Uk Seo, Joo-Youn Cho, Joo-Youn Cho, Wan-Uk Kim, Wan-Uk Kim, Wan-Uk Kim, Donghyun Kim, Donghyun Kim, Donghyun Kim   +25 more
doaj   +1 more source

Association of plasma propionate concentration with coronary artery disease in a large cross-sectional study

Frontiers in Cardiovascular Medicine, 2023
BackgroundMicrobiome has been linked to the pathogenesis of coronary artery disease (CAD) but data providing direct evidence for an association of short-chain fatty acids (SCFA) with CAD are lacking.
Nikolaos Pagonas, Nikolaos Pagonas, Nikolaos Pagonas, Felix S. Seibert, Gerhard Liebisch, Maximillian Seidel, Theodoros Giannakopoulos, Benjamin Sasko, Benjamin Sasko, Oliver Ritter, Oliver Ritter, Nina Babel, Timm H. Westhoff   +12 more
doaj   +1 more source

The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection

Microbiology Spectrum, 2021
Short-chain fatty acids (SCFAs), which consist of six or fewer carbons, are fermentation products of the bacterial community that inhabits the intestine.
Fernanda Pace, Sara E. Rudolph, Ying Chen, Bin Bao, David L. Kaplan, Paula I. Watnick   +5 more
doaj   +1 more source

Effect of Feeding Discarded Durian Peel Ensiled with Lactobacillus casei TH14 and Additives in Total Mixed Rations on Digestibility, Ruminal Fermentation, Methane Mitigation, and Nitrogen Balance of Thai Native–Anglo-Nubian Goats

Fermentation, 2022
The objective of this study was to evaluate the effect of fermented discarded durian peel with Lactobacillus casei TH14, cellulase, and molasses separately or in combination in total mixed rations on feed utilization, digestibility, ruminal fermentation,
Natcha Panyawoot, Sarong So, Anusorn Cherdthong, Pin Chanjula   +3 more
doaj   +1 more source

Prediction of high fecal propionate-to-butyrate ratios using 16S rRNA-based detection of bacterial groups with liquid array diagnostics

BioTechniques, 2023
Butyrate and propionate represent two of three main short-chain fatty acids produced by the intestinal microbiota. In healthy populations, their levels are reportedly equimolar, whereas a deviation in their ratio has been observed in various diseased ...
Pranvera Hiseni, Lars Snipen, Robert C Wilson, Kari Furu, Finn Terje Hegge, Knut Rudi   +5 more
doaj   +1 more source