Rumen microbiota inoculation indicates collaborative mechanisms enhancing propionate supply to alleviate weaning stress in lambs. [PDF]
MicrobiomeChen T +10 more
europepmc +1 more source
The FEBS Journal, EarlyView.The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna +4 more
wiley +1 more source
<i>Mycobacterium tuberculosis</i> growth arrest on propionate at acidic pH is suppressed by mutations in <i>phoPR</i> and pyrazinamide treatment. [PDF]
mBioMurdoch HM +3 more
europepmc +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
The FEBS Journal, EarlyView.Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Short-chain fatty acids in the tumor microenvironment: from molecular mechanisms to cancer therapy. [PDF]
TheranosticsXiang Y, Du A, Wang Z, Pan H, Yuan K.
europepmc +1 more source
Effect of Moderate Heat on TCE Reductive Dechlorination Rates in Groundwater
Groundwater Monitoring &Remediation, EarlyView.Abstract Low‐temperature heating (in the mesophilic range of ~15 to 40 °C) of contaminated aquifers offers the prospect of increasing the rates for biotic and abiotic treatment of volatile organic compounds. Thermal In Situ Sustainable Remediation (TISR®) is one of the approaches available to implement low temperature heating.
David L. Freedman +3 more
wiley +1 more source
Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis
Immunology, EarlyView.Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay +4 more
wiley +1 more source
The Role of Butyrate in People with Metabolic Dysfunction-Associated Steatotic Liver Disease and Related Metabolic Comorbidities: A Systematic Review. [PDF]
Curr Obes RepGonzález-González A +8 more
europepmc +1 more source
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT Climate change has intensified the need to reduce greenhouse gas emissions, particularly methane (CH4) from enteric fermentation. Genetic selection has emerged as a promising mitigation strategy; however, studies on Bos taurus indicus , especially Nellore cattle, remain limited.
J. A. Silva +10 more
wiley +1 more source