Results 11 to 20 of about 192,124 (377)

Propionate and Alzheimer’s Disease [PDF]

Frontiers in Aging Neuroscience, 2021
Propionate, a short-chain fatty acid, serves important roles in the human body. However, our review of the current literature suggests that under certain conditions, excess levels of propionate may play a role in Alzheimer’s disease (AD).
Jessica Killingsworth, D. Sawmiller, R. Shytle   +2 more
semanticscholar   +4 more sources

Predicting butyrate- and propionate-forming bacteria of gut microbiota from sequencing data

Gut Microbes, 2022
The bacteria-derived short-chain fatty acids (SCFAs) butyrate and propionate play important (distinct) roles in health and disease, and understanding the ecology of respective bacteria on a community-wide level is a top priority in microbiome research ...
Berenike Kircher, Sabrina Woltemate, Frank Gutzki, Dirk Schlüter, Robert Geffers, Heike Bähre, Marius Vital   +6 more
doaj   +2 more sources

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro [PDF]

Diabetes, obesity and metabolism, 2016
Aims: Diet-derived short chain fatty acids (SCFAs) improve glucose homeostasis in vivo, but the role of individual SCFAs and their mechanisms of action have not been defined.
Bewick, Gavin, Castañera González, Ramón, Chambers, Edward S., Choudhary, Pratik, Frost, Gary, Hill, Thomas, Huang, Guo Cai, Liu, Bo, Maldonado, Inmaculada Ruz, Morrison, Douglas J., Persaud, Shanta J., Pingitore, Attilio, Preston, Tom, Tedford, Catriona, Wallis, Gareth A.   +14 more
core   +5 more sources

Propionate-Producing Consortium Restores Antibiotic-Induced Dysbiosis in a Dynamic in vitro Model of the Human Intestinal Microbial Ecosystem

Frontiers in Microbiology, 2019
Metabolic syndrome is a growing public health concern. Efforts at searching for links with the gut microbiome have revealed that propionate is a major fermentation product in the gut with several health benefits toward energy homeostasis.
Racha El Hage, Emma Hernandez-Sanabria, Marta Calatayud Arroyo, Ruben Props, Tom Van de Wiele   +4 more
doaj   +2 more sources

Propionate ameliorates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress

Frontiers in Pharmacology, 2016
Propionate is a short chain fatty acid and abundant as butyrate in the gut and blood. However, propionate has been studied less extensively than butyrate in the treatment of colitis.
Lingchang Tong, Lingchang Tong, Yue Wang, Yue Wang, Zhi-bin Wang, Wei-ye Liu, Sheng Sun, Li-chao Zhang, Ding-feng Su, LING LI   +9 more
doaj   +2 more sources

Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice

Frontiers in Microbiology, 2019
Short-chain fatty acids (SCFA) are important dietary and microbiome metabolites that can have roles in gut immunity as well as further afield. We previously observed that gut microbiome alteration via antibiotics led to attenuated lung inflammatory ...
Xiaoli Tian, Judith Hellman, Alexander R. Horswill, Heidi A. Crosby, Kevin P. Francis, Arun Prakash, Arun Prakash   +6 more
doaj   +2 more sources

The common gut microbe Eubacterium hallii also contributes to intestinal propionate formation

Frontiers in Microbiology, 2016
Eubacterium hallii is considered an important microbe in regard to intestinal metabolic balance due to its ability to utilize glucose and the fermentation intermediates acetate and lactate, to form butyrate and hydrogen.
Christina eEngels, Hans-Joachim eRuscheweyh, Niko eBeerenwinkel, Christophe eLacroix, Clarissa eSchwab   +4 more
doaj   +2 more sources

The Structure of Guanine Propionate [PDF]

Journal of Biological Chemistry, 1961
Usama Al-Khalidi, Gordon R. Greenberg
openalex   +3 more sources

The gut metabolite indole-3 propionate promotes nerve regeneration and repair

Nature, 2022
The regenerative potential of mammalian peripheral nervous system neurons after injury is critically limited by their slow axonal regenerative rate1. Regenerative ability is influenced by both injury-dependent and injury-independent mechanisms2.
Elisabeth Serger, Lucia Luengo-Gutierrez, Jessica S. Chadwick, G. Kong, Luming Zhou, Greg Crawford, M. Danzi, A. Myridakis, A. Brandis, Adesola T. Bello, Franziska Müller, Alexandros Sanchez-Vassopoulos, Francesco De Virgiliis, Phoebe Liddell, M. Dumas, J. Strid, S. Mani, Dylan Dodd, S. Di Giovanni   +18 more
semanticscholar   +1 more source

Syntrophic entanglements for propionate and acetate oxidation under thermophilic and high-ammonia conditions

The ISME Journal, 2023
Propionate is a key intermediate in anaerobic digestion processes and often accumulates in association with perturbations, such as elevated levels of ammonia. Under such conditions, syntrophic ammonia-tolerant microorganisms play a key role in propionate
Abhijeet Singh, A. Schnürer, Jan Dolfing, M. Westerholm   +3 more
semanticscholar   +1 more source