Results 21 to 30 of about 192,124 (377)
The ISME Journal, 2022 The human microbiome plays an essential role in the human immune system, food digestion, and protection from harmful bacteria by colonizing the human intestine.
T. Ryu +21 more
semanticscholar +1 more source
Microbiome, 2022 Background Vascular calcification is a major cause of the high morbidity and mortality of cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain fatty acids (SCFAs) are derived from the intestinal microbiota and can
Jianlong Yan +13 more
semanticscholar +1 more source
Deciphering Tryptophan Oxygenation: Key Modulators of 2-Oxindole Formation in MarE. [PDF]
Angew Chem Int Ed EnglThis study reveals that MarE, a heme‐dependent aromatic oxygenase, favors dioxygenation of β‐methyl‐l‐tryptophan in the absence of ascorbate and demonstrates how structural and redox tuning shifts its reactivity toward selective monooxygenation, yielding a 2‐oxindole scaffold. These findings offer new insights into enzyme‐controlled indole oxidation in
Nguyen RC, Shin I, Liu A.
europepmc +3 more sources
Altered propionate metabolism contributes to tumor progression and aggressiveness
Nature Metabolism, 2022 The alteration of metabolic pathways is a critical strategy for cancer cells to attain the traits necessary for metastasis in disease progression. Here, we find that dysregulation of propionate metabolism produces a pro-aggressive signature in breast and
Ana P. Gomes +17 more
semanticscholar +1 more source
Microbiome, 2021 Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived from the gut microbiota, which has the ...
Yan-fang Hou +18 more
semanticscholar +1 more source
European Heart Journal, 2021 AIMS Atherosclerotic cardiovascular disease (ACVD) is a major cause of mortality and morbidity worldwide, and increased low-density lipoproteins (LDLs) play a critical role in development and progression of atherosclerosis.
A. Haghikia +31 more
semanticscholar +1 more source
Nature Communications, 2021 We describe the anaerobic conversion of inositol stereoisomers to propionate and acetate by the abundant intestinal genus Anaerostipes. A inositol pathway was elucidated by nuclear magnetic resonance using [13C]-inositols, mass spectrometry and ...
T. Bui +9 more
semanticscholar +1 more source
METABOLISM OF PROPIONATE BY SHEEP LIVER. OXIDATION OF PROPIONATE BY HOMOGENATES [PDF]
Biochemical Journal, 1965 1. The rate and stability to aging of the metabolism of propionate by sheep-liver slices and sucrose homogenates were examined. Aging for up to 20min. at 37 degrees in the absence of added substrate had little effect with slices, whole homogenates or homogenates without the nuclear fraction. 2.
R. M. Smith, W. S. Osborne-White
openaire +3 more sources
Narasin inclusion for feedlot lambs fed a diet containing high amounts of ground flint corn
Scientia Agricola, 2020 : Narasin is an antibacterial agent that may change rumen fermentation. Two experiments were proposed to evaluate the efficiency of narasin inclusion for lambs fed a diet containing high amounts of ground flint corn.
Daniel Montanher Polizel +9 more
doaj +1 more source
Biology and Life Sciences Forum, 2023 Synbiotics, a combination of prebiotics and probiotics, are growing in popularity, with consumers desiring improved gastrointestinal health. Prebiotics are non-digestible nutrients that can be metabolized by microbiota to exert a beneficial effect, while
Trevor O. Kirby +7 more
doaj +1 more source