Results 31 to 40 of about 192,124 (377)

Propionate alleviates myocardial ischemia-reperfusion injury aggravated by Angiotensin II dependent on caveolin-1/ACE2 axis through GPR41

International Journal on Biological Sciences, 2022
Myocardial ischemia/reperfusion (I/R) injury is still a lack of effective therapeutic drugs, and its molecular mechanism is urgently needed. Studies have shown that the intestinal flora plays an important regulatory role in cardiovascular injury, but the
Fan Deng, Liang Zhang, Han Wu, Y. Chen, Wenqian Yu, Ronghui Han, Yuan Han, Xiao-Qi Zhang, Qishun Sun, Zebin Lin, Yu Wang, Yong-pan Liu, Jingyi Chen, Ke-xuan Liu, Jingjuan Hu   +14 more
semanticscholar   +1 more source

The propionate-GPR41 axis in infancy protects from subsequent bronchial asthma onset

Gut Microbes, 2023
Evidence has accumulated that gut microbiota and its metabolites, in particular the short-chain fatty acid propionate, are significant contributors to the pathogenesis of a variety of diseases.
Takashi Ito, Yumiko Nakanishi, Ryohei Shibata, Noriko Sato, Toshi Jinnohara, Sayo Suzuki, Wataru Suda, Masahira Hattori, Ikuo Kimura, Taiji Nakano, Fumiya Yamaide, Naoki Shimojo, Hiroshi Ohno   +12 more
doaj   +1 more source

Magnesium and imidazole propionate

Clinical Nutrition ESPEN, 2021
Circulating levels of imidazole propionate (ImP), a microbial metabolite of histidine, were higher in participants with type 2 diabetes (T2D) compared to those without and also induced insulin resistance. We hypothesize that low intake of magnesium (Mg) and/or low body Mg status in humans may lead to low Mg concentrations in gut microbiota, and, in ...
Lei Fan, Danxia Yu, Xiangzhu Zhu, Xiang Huang, Harvey J. Murff, M.Andrea Azcarate-Peril, Martha J. Shrubsole, Qi Dai   +7 more
openaire   +3 more sources

Propionate alleviates fatty acid-induced mitochondrial dysfunction, oxidative stress, and apoptosis by upregulating PPARG coactivator 1 alpha in hepatocytes.

Journal of Dairy Science, 2022
Reduced feed intake during the transition period renders cows unable to meet their energy needs for maintenance and lactation, leading to a state of negative energy balance.
Xinghui Wang, Mengyao Zhu, J. Loor, Q. Jiang, Yiwei Zhu, Wei Li, Xiliang Du, Yuxiang Song, W. Gao, Lin Lei, Jianguo Wang, Guowen Liu, Xinwei Li   +12 more
semanticscholar   +1 more source

Inhibition of the Fermentation of Propionate to Methane by Hydrogen, Acetate, and Propionate [PDF]

Applied and Environmental Microbiology, 1990
Inhibition of the fermentation of propionate to methane and carbon dioxide by hydrogen, acetate, and propionate was analyzed with a mesophilic propionate-acclimatized sludge that consisted of numerous flocs (size, 150 to 300 μm). The acclimatized sludge could convert propionate to methane and carbon dioxide stoichiometrically without ...
Naomichi Nishio, Manabu Shobayashi, Satoshi Fukuzaki, Shiro Nagai   +3 more
openaire   +3 more sources

Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods [PDF]

, 2016
Background: Short-chain fatty acids (SCFAs), metabolites produced through the microbial fermentation of nondigestible dietary components, have key roles in energy homeostasis.
Alhabeeb, Habeeb, Busza, Albert, Byrne, Claire S., Chambers, Edward S., Chhina, Navpreet, Fitzpatrick, Julie, Fountana, Sofia, Frost, Gary S., Garcia-Perez, Isabel, Goldstone, Anthony P., Holmes, Elaine, Irani, Cherag, Morrison, Douglas J., Preston, Tom, Tedford, Catriona   +14 more
core   +1 more source

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

New England Journal of Medicine, 2007
BACKGROUND Long-acting beta-agonists and inhaled corticosteroids are used to treat chronic obstructive pulmonary disease (COPD), but their effect on survival is unknown.
P. Calverley, Julie A. Anderson, B. Celli, G. Ferguson, C. Jenkins, P. Jones, J. Yates, J. Vestbo   +7 more
semanticscholar   +1 more source

Formation of propionate and butyrate by the human colonic microbiota.

Environmental Microbiology, 2017
The human gut microbiota ferments dietary non-digestible carbohydrates into short-chain fatty acids (SCFA). These microbial products are utilized by the host and propionate and butyrate in particular exert a range of health-promoting functions.
P. Louis, H. Flint
semanticscholar   +1 more source

Serum Short-Chain Fatty Acids and Associations With Inflammation in Newly Diagnosed Patients With Multiple Sclerosis and Healthy Controls

Frontiers in Immunology, 2021
Multiple sclerosis (MS) is a chronic immune-mediated disease characterized by demyelination and neuroaxonal damage in the central nervous system. The etiology is complex and is still not fully understood.
Anna Olsson, Stefan Gustavsen, Thao Duy Nguyen, Margareta Nyman, Annika R. Langkilde, Tue H. Hansen, Finn Sellebjerg, Annette B. Oturai, Helle Bach Søndergaard   +8 more
doaj   +1 more source

Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans [PDF]

, 2018
Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate ...
Baldwin, Besten, Boets, Canfora, Canfora, Chambers, Chandramouli, De Vadder, Flint, Frayn, Ge, Kimura, Kimura, Kummitha, Ludwig, Morrison, Peters, Psichas, Ridaura, Weir   +19 more
core   +1 more source